Elucidation of molecular mechanisms of mental health improvement following physical exercise and assembly of research resources

2008 Fiscal Year Self-evaluation Report

• Project/Area Number: 18200041
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Sports science
• Research Institution: National Institute of Fitness and Sports in Kanoya
• Principal Investigator: SHIBAYAMA Hidetaro National Institute of Fitness and Sports in Kanoya, 名誉教授 (00162644)
• Project Period (FY): 2006 – 2009
• Keywords: 健康スポーツ科学 / 応用健康科学 / 体力医学 / メンタルヘルス / 運動処方 / 運動療法

Research Abstract

(1) 長期間の運動トレーニングがメンタルヘルスの改善に及ぼす影響を、既存の測定・分析方法とは異なる最新技術で検討し、従来の実験方法では捉えることが出来なかった生体応答から運動による「メンタルヘルス改善」の新たな基準を作成する。
(2) 長期間の運動トレーニング及び一過性の運動が脳神経細胞の構造、機能的変化及び自律神経機能に及ぼす影響を分子・細胞レベルにおいて検討し、運動によるメンタルヘルス改善のメカニズムの一端を明らかにする。
(3) 「メンタルヘルス改善のための運動処方プログラム」を基本とした次世代のプログラム開発に直結する実用的な研究技術・手法の開発を行う。

Research Products

• [Journal Article] Pulse wave velocity for assessment of arterial stiffness among people with spinal cord injury : a pilot study (2009)
  • Author(s): Miyatani, M., 他5名
  • Journal Title: J. Spinal Cord Med. Pages: 72-78
  • Peer Reviewed
• [Journal Article] Age-related changes in two- and three-dimensional morphology of type-identified endplates in the rat diaphragm (2009)
  • Author(s): Suzuki T., 他4名
  • Journal Title: J. Physiol. Sci. 59 Pages: 57-62
  • Peer Reviewed
• [Journal Article] Differential cell death regulation between adult-unloaded and aged rat soleus muscle (2009)
  • Author(s): Ogata T., 他4名
  • Journal Title: Mech. Aging Develop. 130 Pages: 328-336
  • Peer Reviewed
• [Journal Article] Resistance training in men is associated with increased arterial stiffness and blood pressure but does not adversely affect endothelial function as measured by arterial reactivity to the cold pressor test. Exp (2008)
  • Author(s): Kawano, H., 他7名
  • Journal Title: Physiol. 93 Pages: 296-302
  • Peer Reviewed
• [Journal Article] Bidirect signaling between calcium channels of skeletal muscle requires multiple direct and indirect interactions (2006)
  • Author(s): Sheridan, D.C., 他5名
  • Journal Title: Proc. Natl. Acad. Sci.USA, reviewed 103 Pages: 19760-19765
  • Peer Reviewed
• [Presentation] The impaired inflammatory response to muscle damage contributes to the impaired muscle regenerative capacity and to increased muscle adiposity with aging (2008)
  • Author(s): Machida, S., Okamoto T.
  • Organizer: The Integrative Biology of Exercise V
  • Place of Presentation: South Carolina, USA
  • Year and Date: 20080900
• [Presentation] Alterations of trabecular bone architecture and muscle atrophy after sciatic neurectomy in rat proximal tibiae (2008)
  • Author(s): Tamaki, H., 他3名
  • Organizer: 12^<th> Annual Congress ECSS
  • Place of Presentation: Jyvaskyla, Finland
  • Year and Date: 20080700
• [Presentation] Poor flexibility is associated with Arterial Stiffening (2007)
  • Author(s): Yamamoto, K., 他9名
  • Organizer: ACSM 54^<th> Annual Meeting
  • Place of Presentation: New Orleans, USA.
  • Year and Date: 20070500
• [Presentation] A novel form of retrograde signaling between RyR3 and the DHPR in skeletal muscle (2007)
  • Author(s): Sheridan, D.C., 他5名
  • Organizer: 51^<st> Annual Meering of the Biophysical Society
  • Place of Presentation: Baltimore, USA.
  • Year and Date: 20070200
• [Presentation] Relation between hippocampal structure and psychological well-being in exercising and non-exercising students (2006)
  • Author(s): Fujimoto, T., 他10名
  • Organizer: 11h Annual Congress ECSS
  • Place of Presentation: Lausanne, Switzerland
  • Year and Date: 20060700