2009 Fiscal Year Final Research Report
Validation of OMICS data of urological malignancies for the clinical use
| Project/Area Number |
18209049
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Kyoto University |
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Principal Investigator |
OGAWA Osamu Kyoto University, 大学院・医学研究科, 教授 (90260611)
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| Co-Investigator(Kenkyū-buntansha) |
NISHIYAMA Hiroyuki 京都大学, 大学院・医学研究科, 准教授 (20324642)
INUI Kenichi 京都大学, 大学院・医学研究科, 教授 (70034030)
FUKUSHIMA Masanori 京都大学, 大学院・医学研究科, 教授 (80107820)
TUJIMOTO Gouzo 京都大学, 大学院・薬学研究科, 教授 (80172013)
NAKAMURA Eijiro 京都大学, 大学院・医学研究科, 講師 (90293878)
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| Project Period (FY) |
2006 – 2009
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| Keywords | 泌尿器科癌 / OMICS / 遺伝子解析 / 網羅的発現解析 / プロテオーム |
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| Research Abstract |
In this project we aimed to carry out experiments which were essential for application of our achieved findings to clinical settings. First, we developed a comprehensive database incorporating genomic data including gene polymorphism, transcriptome data, and proteomic data. Second, we explored novel molecular targets for diagnosis or treatment by analyzing this database and clinical information. Finally, functions and roles of the molecules were investigated using in-vitro and in-vivo experimental models.
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