2009 Fiscal Year Final Research Report
Studies on the transmission and pathobiology of New and Old World leishmaniases
| Project/Area Number |
18256004
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Parasitology (including Sanitary zoology)
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| Research Institution | Kochi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
UEZATO Hiroshi 琉球大学, 医学部, 教授 (60160157)
KATAKURA Ken 北海道大学, 大学院・獣医医学研究科, 教授 (10130155)
MIMORI Tatsuyuki 熊本大学, 医学部, 教授 (00117384)
ITO Makoto 愛知医科大学, 医学部, 教授 (90137117)
KATO Hirotomo 山口大学, 農学部, 准教授 (00346579)
KORENAGA Massataka 高知大学, 医学部, 准教授 (00128274)
YMMAMOTO Yu-ichi 琉球大学, 医学部, 助教 (00363672)
MANUEL Calvopina 高知大学, 医学部, 助教 (20346711)
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| Project Period (FY) |
2006 – 2009
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| Keywords | 国際交流研究 / エクアドル:ペルー:アルゼンチン:パキスタン:バングラデシュ / リーシュマニア症 / 媒介サシチョウバエ / 伝播疫学 / 分子生物学 / 病態生理 / Leishmania原虫感染 |
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| Research Abstract |
Leishmaniasis is one of the protozoan infectious diseases transmitted by blood-sucking insects, sandflies. The disease is widely distributed, affecting at least 12 million people in 88 countries of the world. In this study, three disease factors, patients, vector sandflies, and reservoir animals, were investigated by employing molecular biological, immunological and epidemiological methods. Main results obtained are as follows : (1) relation between Leishmania spp. and disease forms, (2) determination of vector species, (3) search for different mammals infected with Leishmania, (4) development of rapid diagnosis and treatment, (5) search for control measures at each endemic area.
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[Journal Article] A survey of cutaneous leishmaniasis at village Gaibi Dero, District Larkana, Sindh, Pakistan2010
Author(s)
Farooq R. Soomro, Ghuram M. Pathan, Parvez Abbasi, Doulat Bajaj, Nuzhat S. Bhartti, Javed Hussain, Abdul M. Bhutto, Yoshihisa Hashiguchi
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Journal Title
Gomal Journal of Medical Science 7
Pages: 137-139
Peer Reviewed
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[Journal Article] Population structure and geographical subdivision of the Leishmania major vector Phelebotomus papatasi as revealed by microsatellite variation2009
Author(s)
Omar Hamarsheh, W. Presber, M.R. Yaghoobi-Ershadi, A. Amro, A. AL-Jawabreh, S. Sawalha, A. AL-Lahem, M.L. Das, S. Guernaoui, N. Seridi, R.C. Dhiman, Yoshihisa Hashiguchi, J. Ghrab, M. Hassan, G. Schonian
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Journal Title
Medical and Veterinary Entomology 23
Pages: 69-77
Peer Reviewed
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[Journal Article] Polymorphisms of cytochrome b gene in Leishmania parasites and their relation to types of cutaneous leishmaniasis lesions in Pakistan2008
Author(s)
Chomar Kaung Myint, Yutaka Asato, Yu-ichi Yamato, Hirotomo Kato, Abdul M. Bhutto, Farooq R. Soomro, Muhamad Z. Momen, Jun Mataumoto, Jorge D. Marco, Minoru Oshiro, Ken Katakura, Yoshihisa Hashiguchi, Hiroshi Uezato
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Journal Title
Journal of Dermatology 35
Pages: 76-85
Peer Reviewed
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[Journal Article] The identification of sandfly species, from an area of Argentina with endemic leishmaniasis, by the PCR-based analysis of the gene coding for 18S ribosomal RNA2007
Author(s)
Paola Andrea Barroso, Jorge D. Marco, Hirotomo Kato, R. Tarama, P. Rueda, S.P. Cajal, Miguel A. Basombrio, Masataka Korenaga, N.J. Taranto, Yoshihisa Hashiguchi
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Journal Title
Annals of Tropical Medicine and Parasitology 101
Pages: 247-253
Peer Reviewed
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[Journal Article] Multilocus enzyme electrophoresis and cytochrome b gene sequencing-based identification of Leishmania isolates from different foci of cutaneous leishmaniasis in Pakistan2006
Author(s)
Marco, J.D., Bhutto, A.M., Soomro, F.R., Baloch, J.H., Barroso, P.A., Hirotomo Kato, Hiroshi Uezato, Ken Katakura, Masataka Korenaga, Sigeo Nonaka, Yoshihisa Hashiguchi
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Journal Title
American Journal of Tropical Medicine and Hygiene 75
Pages: 261-266
Peer Reviewed
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[Journal Article] Leishmania isoenzyme polymorphisms in Ecuador: Relationships with geographic distribution and clinical presentation2006
Author(s)
Manuel Calvopina, Rodrigo X Armijos, Jorge D. Marco, Hiroshi Uezato, Hirotomo Kato, Eduardo A Gomez, Masataka Korenaga, Paola A Barroso, Tatsuyuki Mimori, Philip J Cooper, Shigeo Nonaka, Yoshihisa Hashiguchi
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Journal Title
BMC Infectious Diseases 6
Pages: 1-9
Peer Reviewed
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