2007 Fiscal Year Final Research Report Summary
Intakes of vitamins and carotenoids and prostate cancer risk in a case-control study
| Project/Area Number |
18590624
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Miyagi Cancer Center Research Institute |
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Principal Investigator |
YOSHIKAZU Nishino Miyagi Cancer Center Research Institute, Division of Epidemiology, Senior Chief Researcher (70302099)
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| Co-Investigator(Kenkyū-buntansha) |
MINAMI Yuko Tohoku University Graduate School of Medicine, Health Sciences, Professor (60239316)
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| Project Period (FY) |
2006 – 2007
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| Keywords | Prostate cancer / carotenoids / vitamins / case-control study / enidemiology / vegetables / fruit / Japan |
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| Research Abstract |
To elucidate the associations of dietary vitamins and carotenoids intakes with prostate cancer risk in Japanese men, we conducted a hospital-based case-control study. Study subjects consisted of 260 prostate cancer cases and 1599 male hospital controls, aged 50 and over admitted to a single hospital (Miyagi Cancer Center). Information on diet was collected using a self administered tad frequency questionnaire (FFQ) including 40 food items. We developed a food composition table that corresponded to the items listed in the questionnaire, and calculated daily vitamins and carotenoids intakes by multiplying the consumption frequency of each food by the nutrient content of the assigned portion size and summing these values for all foods. The risk of prostate cancer for the intakes of vitamins and carotenoids were assessed using unconditional logistic regression analysis adjusted for year of birth, year of survey, area of residence, referral base, smoking history, history of alcohol drinking family history of prostate cancer in parents and siblings, occupational history, total caloric intake and height We also investigated the risk for related vegetables and fruits intakes. There was no association between prostate cancer risk and dietary intakes of a -carotene, β -carotene, cryptoxanthin, vitamin D, α-tocopherols, vitamin B_6 vitamin B_12, folate, and ascorbic acid. As for vegetables and fruits, Intake of Chinese cabbage was inversely associated with the prostate cancer risk and decreasing risk of advanced prostate cancer was associated with increasing intake of green vegetables. The association between cruciferous vegetables and prostate cancer risk should be explored in further studies.
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[Presentation] Height and prostate cancer risk2008
Author(s)
Yuko Minami, Yoshikazu Nishino
Organizer
The 18th annual scientific meeting of the Japan Epidemiological Association
Place of Presentation
Tokyo
Year and Date
2008-01-26
Description
「研究成果報告書概要(欧文)」より
