• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2008 Fiscal Year Final Research Report

Search for novel markers, and mechanisms of tumorigenesis and treatment responsiveness of central nervous system germ cell tumors

Research Project

  • PDF
Project/Area Number 18591605
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Cerebral neurosurgery
Research InstitutionSaitama Medical University

Principal Investigator

MATSUTANI Masao  Saitama Medical University, 医学部, 教授 (90010454)

Co-Investigator(Kenkyū-buntansha) NISHIKAWA Ryo  埼玉医科大学, 医学部, 教授 (90237678)
Project Period (FY) 2006 – 2008
Keywords胚細胞腫瘍 / 腫瘍マーカー
Research Abstract

:頭蓋内胚細胞腫瘍の凍結標本を用いたcDNA array による遺伝子発現解析を行いった.Germinoma に比べてnon-greminomatous germ cell tumor において有意に発現の高い遺伝子としてBone Morphogenetic Protein-4,SOX-11,Frizzled 7 をピックアップした.免疫組織化学染色による蛋白質発現の解析を行って,新規腫瘍マーカーとしての可能性を検討した.

URL: 

Published: 2010-06-10   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi