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2007 Fiscal Year Final Research Report Summary

Effect of Helicobacter pylori eradication on sleep bruxism, periodontal disease and oral malodor

Research Project

Project/Area Number 18592250
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionKagoshima University

Principal Investigator

OHMURE Haruhito  Kagoshima University, Graduate School of Medical and Dental Sciences, Assistant Professor (00404484)

Co-Investigator(Kenkyū-buntansha) MIYAWAKI Shouichi  Kagoshima University, Graduate School of Medical and Dental Sciences, Professor (80295807)
TSUBOUCHI Hirohito  Kagoshima University, Graduate School of Medical and Dental Sciences, Professor (60145480)
NAGATA Junko  Kagoshima University, Graduate School of Medical and Dental Sciences, Assistant Professor (50264429)
Project Period (FY) 2006 – 2007
Keywordsgastro-oesonhaeeal reflux / sleep bruxism / Helicobacter pylori / eradication / duodenogastro-esophageal reflux / DGOR
Research Abstract

The purpose of this study was to investigate the effect of Helicobacter pylori infection on the periodontal disease, oral malodor and general health status.
One hundred and five adults were recruited from the patient who visited Kagoshima University Hospital. As the purpose of the present study, subjects were divided into two groups according to the presence or absence of gastro-oesophageal reflux (GERD) manifestations. Gastro-oesophageal manifestations were evaluated using the Carlsson-Dent self-administered questionnaire (QUEST) and frequency scale for the symptoms of GERD (FSSG).General and oral conditions were compared between the groups. As the result, 25.7% of subjects were diagnosed as a GERD positive. The prevalence of respiratory symptoms, back pain, numbness of hand, urological manifestations and sleep disorder in the GERD positive group were greater than that in the GERD negative group. Subjective QOL determined by WHO QOL 24 in the GERD positive group were lower than that in the GERD negative group.
The infection of Helicobacter pylori ware determined by 13C-urea breath test. Three of 15 subjects had an infection of Helicobacter pylori. As the result of polysomnography and pH monitoring in the oesophagus and stomach, sleep bruxism episode occurred during the decrease of intro-oesophageal pH and increase of intra-gastric pH.

  • Research Products

    (14 results)

All 2008 2007 2006

All Journal Article (10 results) (of which Peer Reviewed: 2 results) Presentation (3 results) Book (1 results)

  • [Journal Article] Influence of Forward Head Posture on Condylar Position2008

    • Author(s)
      H.Ohmure, S.Mivawaki, J.Nagata, et. al.
    • Journal Title

      Journal of OralRehabiltation (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Changes in stomatognathic function after orthodontic treatment combined with mandibular distraction osteogenesis2008

    • Author(s)
      Maeda A, Soejima K, Ogura M, Ohmure H, Sugihara K, Miyawaki S
    • Journal Title

      Angle Orthod (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Influence of Forward Head Posture on Condylar Position2008

    • Author(s)
      H. Ohmure, S. Miyawaki, J. Nagata, et. al.
    • Journal Title

      Journal of Oral Rehabiltation (in press)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Changes in stomatognathic function after orthodontic treatment combined with mandibular distraction osteogenesis2008

    • Author(s)
      Maeda, A., Soejima, K., Ogura, M., Ohmure, H., Sugihara, K., Miyawaki, S
    • Journal Title

      Angle Orthod (in press)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] 睡眠時ブラキシズムの関連因子2007

    • Author(s)
      宮脇 正一, 永田 順子, 大牟禮 治人, 他
    • Journal Title

      心療内科 11

      Pages: 278-284

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Sleep bruxism and gastro-oesophageal reflux2007

    • Author(s)
      S. Miyawaki
    • Journal Title

      Pharma Medica 25

      Pages: 70-84

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] New factors associated with sleep bruxism2007

    • Author(s)
      S. Miyawaki
    • Journal Title

      Shinryou Naika 11

      Pages: 278-284

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] New factors associated with sleep bruxism -swallow and gastroesophageal reflux-2006

    • Author(s)
      S. Miyawaki
    • Journal Title

      Ann. Kagoshima Dent 26

      Pages: 1-8

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Sleep bruxism frequently observed in children : New gastroenterological approach2006

    • Author(s)
      S. Miyawaki
    • Journal Title

      J. Jpn. Soc. Stomatognath. Funct 13

      Pages: 16-20

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Occlusal force and condylar motion in patients with anterior open bite2006

    • Author(s)
      S. Miyawaki
    • Journal Title

      ShikaRinsyouKenkyu 1

      Pages: 81-86

    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Relationship between forward head posture and condylar position2008

    • Author(s)
      H.OHMURE, J.NAGATA, S.MIYAWAKI, et. al.
    • Organizer
      Mouth and Face Forum 2008 -in silico dentistry-
    • Place of Presentation
      大阪
    • Year and Date
      20080414-15
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Relationship between forward head posture and condylar position2008

    • Author(s)
      H. Ohmure, J. Nagata, S. Miyawaki, et. al.
    • Organizer
      Mouth and Face Forum 2008
    • Place of Presentation
      Osaka
    • Year and Date
      20080114-15
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Shitsumonshityousa niyoruisyokudo us a nn gyakuryu usyo unoumutokoukuushikka nntonokanren2007

    • Author(s)
      R. Togawa, J. Nagata, H. Ohmure, S. Miyawaki, et. al.
    • Organizer
      The 2nd Annual Meeting of Kyusyu Orthodontic Society
    • Place of Presentation
      Miyazaki
    • Year and Date
      20070217-18
    • Description
      「研究成果報告書概要(欧文)」より
  • [Book] MFF 2008 PROCEEDINGS2008

    • Author(s)
      H.OHMURE, J.NAGATA, S.MIYAWAKI, et. al.
    • Total Pages
      196
    • Publisher
      Medigit
    • Description
      「研究成果報告書概要(和文)」より

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Published: 2010-02-04  

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