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2022 Fiscal Year Final Research Report

Comprehensive analysis of amniotic fluid microbiota for the prevention of preterm delivery: a fundamental study

Research Project

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Project/Area Number 18K09306
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 56040:Obstetrics and gynecology-related
Research InstitutionKurume University

Principal Investigator

Yoshizato Toshiyuki  久留米大学, 医学部, 教授 (80264034)

Project Period (FY) 2018-04-01 – 2023-03-31
Keywords腟細菌叢 / 網羅的解析 / 妊娠
Outline of Final Research Achievements

The vaginal microbiota during pregnancy, specifically the predominance of specific Lactobacillus species and the decrease in overall diversity, contribute to the maintenance of a healthy pregnancy. Conversely, a decrease in Lactobacillus quantity and an increase in microbiota diversity are indicative of bacterial vaginosis, which can be associated with factors such as a history of uterine surgeries and various known factors, including smoking.

Free Research Field

早産、超音波診断

Academic Significance and Societal Importance of the Research Achievements

本研究の成果は、早産に至る妊婦の腟細菌叢を妊娠初期に解析することより、その発症の予測および予防のための戦略を立てる上での基礎的データを提供するものと考えられる。

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Published: 2024-01-30  

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