The improvement for oral appliances to achieve high-level compliance in patients with OSAS

2022 Fiscal Year Final Research Report

• Project/Area Number: 18K09688
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 57050:Prosthodontics-related
• Research Institution: Kyushu Dental College
• Principal Investigator: Makihara Eri 九州歯科大学, 歯学部, 講師 (30433402)
• Co-Investigator(Kenkyū-buntansha): 宮嶋 隆一郎 九州歯科大学, 歯学部, 助教 (30773379) ; 渡辺 崇文 九州歯科大学, 歯学部, 助教 (10845390) ; 鱒見 進一 九州歯科大学, 歯学部, 教授 (70181659)
• Project Period (FY): 2018-04-01 – 2023-03-31
• Keywords: 閉塞性睡眠時無呼吸症 / 口腔内装置 / 治療顎位 / 装着感 / 睡眠状態

Outline of Final Research Achievements

Eight Patients with OSA responses regarding sensation and sleeping conditions when each two types of appliance was fitted were compared. Almost patients preferred soft-type OA, which is more comfortable to wear to and less pain and discomfort to hard-type OA.
Thirty-two patients with OSA were randomly allocated to receive a 50% mandibular advancement or a 75% mandibular advancement with an OA. There was no significant difference in treatment effectiveness between groups. For patients with mild to moderate OSA, 50% mandibular advancement is recommended as the initial therapeutic mandibular position. It was suggested that gender differences also affect treatment effectiveness.

Free Research Field

歯学

Academic Significance and Societal Importance of the Research Achievements

閉塞性睡眠時無呼吸（Obstructive sleep apnea：OSA)に対し歯科では口腔内装置（Oral appliance:OA)治療を行うが，OAの副作用により使用困難な患者が存在する．
そこで，患者にとって受け入れられやすいOAの改良を行うために材質による装着感を比較したところ，硬質素材より軟性素材のOAの方が受け入れられやすいことがわかった．また，下顎50％前方位と75%前方位におけるOAの治療効果を比較したところ，治療効果に有意差が認められなかったことから，初期的なOAの治療顎位は，より顎関節部への負担が少ない下顎50％位で十分であることが示唆された．