Impact of modifiable lifestyle factors on outcomes after breast cancer diagnosis: the Setouchi Breast Cancer Cohort Study

2020 Fiscal Year Final Research Report

• Project/Area Number: 18K10066
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
• Research Institution: Okayama University
• Principal Investigator: Taira Naruto 岡山大学, 大学病院, 准教授 (50467734)
• Project Period (FY): 2018-04-01 – 2021-03-31
• Keywords: 乳がん / ライフスタイル / 身体活動性 / 喫煙 / 予後 / 二次がん / QOL

Outline of Final Research Achievements

The purpose of this study is modifiable life style (diet, exercise, obesity, sleep, drinking, smoking, etc.) and alternative therapies after initial treatment for breast cancer, followed by breast cancer outcomes (recurrence, death, treatment-related complications, health-related QoL). And to clarify the effect on the development of secondary cancer. A multicenter cohort study aimed at verifying the association between lifestyle after breast cancer diagnosis and breast cancer outcomes was conducted, and 1942 cases were enrolled in February 2018. A follow-up survey is currently underway, and the analysis results will be reported in 2023.

Free Research Field

乳がん

Academic Significance and Societal Importance of the Research Achievements

本研究成果により、乳がん診断後のライフスタイルと乳がんアウトカム（再発・死亡・二次がんなど）との関連性に関して、エビデンスレベルの高い知見が得られるものと期待している。これらの科学的根拠に基づき、乳がん患者に対し、推奨されるライフスタイルに関して、適切な提言ができ、社会的な意義は大きいと考えららえる。