Evaluation of the lung injury and ventilation by dynamic CT and Electrical impedance tomography

2021 Fiscal Year Final Research Report

• Project/Area Number: 18K16506
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 55060:Emergency medicine-related
• Research Institution: Yamagata University
• Principal Investigator: Onodera Yu 山形大学, 医学部, 助教 (30594329)
• Project Period (FY): 2018-04-01 – 2022-03-31
• Keywords: ARDS / EIT / Dynamic CT

Outline of Final Research Achievements

This project was to investigate the relation between ventilation and anatomical change of ARDS lung. We used Electrical Impedance Tomography (EIT) to evaluate ventilation and dynamic CT to evaluate anatomical change during ventilation. Due to COVID-19 pandemic, we were only able to enroll few patients. Form these data from few patients, we noticed that regularly applied mechanical ventilation had small change in CT (CT value and movement). This data will be useful for planning future experiment to have specific ventilation mode to have enough signal to be detected and to be evaluated by dynamic CT.

Free Research Field

集中治療

Academic Significance and Societal Importance of the Research Achievements

新たなモニタリング機器を用いる事で障害を受けた肺が人工呼吸される際どのように換気されているか及びどのような解剖学的変化が生じているのか評価し、より障害の少ない呼吸管理法の検討を行う予定だったがCOVID-19のパンデミックの影響で数例のみしかデータを集めることができなかった。しかし得られた数例の所見から将来的に研究を進めるにあたって土台となるデータを得ることができた。