Elucidation of the mechanism of reciprocal Ia inhibition and recurrent inhibition leading to excessive co-contraction

2019 Fiscal Year Final Research Report

• Project/Area Number: 18K17769
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 59010:Rehabilitation science-related
• Research Institution: Niigata University of Health and Welfare
• Principal Investigator: Hirabayashi Ryo 新潟医療福祉大学, リハビリテーション学部, 助教 (60804375)
• Project Period (FY): 2018-04-01 – 2020-03-31
• Keywords: 脊髄相反性抑制 / 筋電図 / 同時収縮 / H反射 / 電気刺激

Outline of Final Research Achievements

The purpose of this study was to determine the relationship between spinal reciprocal inhibition during co-contractions in a two-year project.Two experiments were performed and revealed that spinal reciprocal inhibition was modulated depending on the co-contraction intensity and the muscle activity ratio of the antagonist muscles to each other.It has been reported that spinal reciprocal inhibition disappears with co-contractions, but spinal reciprocal inhibition remains with co-contraction intensity, indicating that the ability to perform joint movements remains during moderate co-contractions.
These research results were published in two international journals and one domestic journal, and 10 conference presentations were made.

Free Research Field

神経生理学

Academic Significance and Societal Importance of the Research Achievements

本研究の知見は，同時収縮中の脊髄にある運動制御の機能を相反性抑制に着目して解明した．本研究は，これまで明らかにされていなかった，低強度の同時収縮中は脊髄相反性抑制の機能が残存することを発見しました．また，その機能葉、拮抗筋同士の筋活動比に依存することも新規性が高い知見となった．この基礎的知見を応用して，同時収縮中の運動パフォーマンスの検討，中枢疾患や高齢者で引き起こされる過剰な同時収縮の治療法として役立つ可能性があると考えている．