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2019 Fiscal Year Final Research Report

Towards the development of intrapulmonary vaccine for cancer

Research Project

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Project/Area Number 18K19401
Research Category

Grant-in-Aid for Challenging Research (Exploratory)

Allocation TypeMulti-year Fund
Review Section Medium-sized Section 47:Pharmaceutical sciences and related fields
Research InstitutionOsaka University

Principal Investigator

Yoshioka Yasuo  大阪大学, 微生物病研究所, 特任准教授(常勤) (00392308)

Project Period (FY) 2018-06-29 – 2020-03-31
Keywords機能性ペプチド / ワクチン
Outline of Final Research Achievements

In the present project, we tried to develop intrapulmonary vaccine system for cancer vaccine. Although we did not reach the goal, we believe that our system will not only provide novel vaccine system for cancer but may also shed light on a novel tool for directing the biodistribution of drugs to specific cell types, such as immune cells.

Free Research Field

医療薬学

Academic Significance and Societal Importance of the Research Achievements

インフルエンザに対する経鼻ワクチンは海外で既に使用されており、粘膜ワクチンによる感染症ワクチンの開発は世界規模で進められている。しかし、経肺ワクチンにより粘膜面のがんを効率的に治療しようとする発想はこれまで盲点であり、本研究を継続することで、新たな治療戦略に向けた基礎治験が得られるものと期待される。

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Published: 2021-02-19  

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