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2009 Fiscal Year Final Research Report

Analysis of between-species and intra-species diversity using primate genome data and application to conservation biology

Research Project

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Project/Area Number 19207008
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Biodiversity/Systematics
Research InstitutionNational Institute of Genetics

Principal Investigator

SAITOU Naruya  National Institute of Genetics, 集団遺伝研究系, 教授 (30192587)

Co-Investigator(Kenkyū-buntansha) ISHIDA Takafumi  東京大学, 大学院・理学系研究科, 准教授 (20184533)
Project Period (FY) 2007 – 2009
Keywords霊長類 / DNA多型 / ゲノム解析 / 保全生物学 / 種間交雑
Research Abstract

For primate conservation biology and for intraspecies diversity study, we developed database called "Prim-Prim". Through comparison of human and macaque genomic sequences, intronic regions sandwitched with identical exonic sequences between two species were extracted, and 2,303 primer pairs which can amplify DNA fragment of unsequenced primate genomes were listed in this database, and it is open to public. We used these primers to determine nucleotide sequences of 6 gibbon species, and showed usefulness of these primers.

  • Research Products

    (19 results)

All 2010 2009 2008 2007 Other

All Journal Article (11 results) (of which Peer Reviewed: 10 results) Presentation (5 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Variations in the coding region of the agouti signaling protein gene do not explain agouti/non-agouti phenotypes in macaques.2010

    • Author(s)
      Nakayama, K., Shotake, T., Takenaka, O., Ishida, T.
    • Journal Title

      Journal of Mammalian Evolution (in press)

    • Peer Reviewed
  • [Journal Article] Study of cynomolgus monkey (Macaca fascicularis) DRA polymorphism in four populations.2010

    • Author(s)
      Aarnink A., Estrade L., Apoil P.A., Kita Y.F., Saitou N., Shiina T., Blancher A.
    • Journal Title

      Immunogenetics 62(3)

      Pages: 123-136

    • Peer Reviewed
  • [Journal Article] Phylogenetic relationships and divergence dates of the whole mitochondrial genome sequences among three gibbon genera.2010

    • Author(s)
      Matsudaira, K., Ishida, T.
    • Journal Title

      Molecular Phylogenetics and Evolution 55

      Pages: 454-459

    • Peer Reviewed
  • [Journal Article] Relic of ancient recombinations in gibbon ABO blood group genes deciphered through phylogenetic network analysis.2009

    • Author(s)
      Kitano T., Noda R., Takenaka O., Saitou N.
    • Journal Title

      Molecular Phylogenetics and Evolution 51

      Pages: 465-471

    • Peer Reviewed
  • [Journal Article] Variable number of tandem repeat polymorphisms of DRD4: re-evaluation of selection hypothesis and analysis of association with schizophrenia.2009

    • Author(s)
      Hattori E., Nakajima M., Yamada K., Iwayama Y., Toyota T., Saitou N., Yoshikawa T.
    • Journal Title

      European Journal of Human Genetics 17

      Pages: 793-801

    • Peer Reviewed
  • [Journal Article] 霊長類の種内変異を解析するためのPCRプライマーデータベースPrim-Primの開発とその応用.2009

    • Author(s)
      斎藤成也, 鈴木留美子, 河合洋介, 石田貴文
    • Journal Title

      DNA多型 17

      Pages: 63-65

  • [Journal Article] Skewed matrilineal genetic composition in a small wild chimpanzee community.2009

    • Author(s)
      Shimada M.K., Hayakawa S., Fujita S., Sugiyama Y., Saitou N.
    • Journal Title

      Folia Primatologica 80(1)

      Pages: 19-32

    • Peer Reviewed
  • [Journal Article] Mitochondrial DNA sequence phylogeny of four populations of the widely distributed cynomolgus macaque (Macaca fascicularis fascicularis).2008

    • Author(s)
      Blancher A., Bonhomme M., Crouau-Roy B., Terao K., Kitano T., Saitou N.
    • Journal Title

      Journal of Heredity 99(3)

      Pages: 254-264

    • Peer Reviewed
  • [Journal Article] Natural selection in the TRL-related genes in the course of primate evolution.2008

    • Author(s)
      Nakajima, T., Ohtani, H., Satta, Y., Uno, Y., Akari, H., Ishida, T., Kimura, A.
    • Journal Title

      Immunogenetics 60

      Pages: 727-735

    • Peer Reviewed
  • [Journal Article] Variation of the melanocortin 1 receptor gene in the macaques.2008

    • Author(s)
      Nakayama, K., Shotake, T., Takenaka, O., Ishida, T.
    • Journal Title

      American Journal of Primatology 70

      Pages: 778-785

    • Peer Reviewed
  • [Journal Article] Mosaic genealogy of the Mus musculus genome revealed by 21 nuclear genes from its three subspecies.2008

    • Author(s)
      Liu Y.-H., Takahashi A., Kitano T., Koide T., Shiroishi T., Moriwaki K., Saitou N.
    • Journal Title

      Genes and Genetic Systems 83

      Pages: 77-88

    • Peer Reviewed
  • [Presentation] 霊長類の種内変異を解析するためのPCRプライマーデータベースPrim-Primの開発とその応用2008

    • Author(s)
      斎藤成也
    • Organizer
      日本DNA多型学会第17回学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-21
  • [Presentation] 霊長類ゲノム多様性解析のためのPrim-Prim DBの開発とその応用2008

    • Author(s)
      斎藤成也
    • Organizer
      日本人類学会第62回大会
    • Place of Presentation
      名古屋市
    • Year and Date
      2008-11-01
  • [Presentation] トコンドリアゲノム配列を用いたHylobatesとSymphalangusの分岐年代推定2008

    • Author(s)
      松平一成, 石田貴文
    • Organizer
      日本霊長類学会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-05
  • [Presentation] Utility of phylogenetic network for deciphering nucleotide sequence history2008

    • Author(s)
      Saitou N
    • Organizer
      NIG International Symposium
    • Place of Presentation
      東京
    • Year and Date
      2008-03-28
  • [Presentation] Evolutionary analysis on primates2007

    • Author(s)
      Saitou N
    • Organizer
      79th Annual Meeting of the Genetics Society of Japan
    • Place of Presentation
      岡山市
    • Year and Date
      2007-09-21
  • [Book] 絵でわかる人類の進化2009

    • Author(s)
      斎藤成也
    • Total Pages
      192
    • Publisher
      講談社サイエンティフィック
  • [Book] ゲノム進化学入門2007

    • Author(s)
      斎藤成也
    • Total Pages
      257
    • Publisher
      共立出版
  • [Remarks]

    • URL

      http://sayer.lab.nig.ac.jp/index-j.htmlhttp://sayer.lab.nig.ac.jp/~saitou/index-j.html

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Published: 2011-06-18   Modified: 2016-04-21  

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