2009 Fiscal Year Final Research Report
Development of Innovative Radical Reactions by Means of Species Hybridization
| Project/Area Number |
19350051
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Osaka Prefecture University |
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Principal Investigator |
RYU Ilhyong Osaka Prefecture University, 理学系研究科, 教授 (80210821)
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| Co-Investigator(Kenkyū-buntansha) |
FUKUYAMA Takahide 大阪府立大学, 理学系研究科, 講師 (60332962)
MATSUBARA Hiroshi 大阪府立大学, 理学系研究科, 准教授 (20239073)
KOBAYASHI Shoji 大阪府立大学, 理学系研究科, 助教 (30374903)
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| Project Period (FY) |
2007 – 2009
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| Keywords | ラジカル反応 / ハイブリッド型連鎖反応 / 環境調和型反応プロセス / イオン反応 / 遷移金属触媒反応 / カルボニル化反応 |
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| Research Abstract |
This research aimed at development of new radical reactions in which both radical species and non-radical species play a key role. Borohydride reagents proved to function as efficient radical mediators. As a notable example, hydroxymethylation of iodoalkanes proceeded using atmospheric pressure of CO and tertrabutylammonium borohydride. Under photo-irradiation conditions, in the presence of Pd complexes, three component coupling reaction of iodoalkanes, CO and terminal alkynes proceeded efficiently to give good yields of acetylenic ketones. Lactol forming reaction was also attained via ionic trapping of acyl radicals by an internal hydroxy group.
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Research Products
(37 results)
