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2009 Fiscal Year Final Research Report

Development of therapy killing or activating targeted cells using bio-techniques

Research Project

  • PDF
Project/Area Number 19360378
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Biofunction/Bioprocess
Research InstitutionChubu University

Principal Investigator

KOBAYASHI Takeshi  Chubu University, 応用生物学部, 教授 (10043324)

Project Period (FY) 2007 – 2009
Keywordsがん / バイオテクノロジー / マグネタイト微粒子 / 温熱療法 / 加温 / リポソーム
Research Abstract

I have developed a new cancer hyperthermia using magnetic nanoparticles. Combination therapy with injection of imiquimod well known as immuno-inducer and hyperthermia was synergistic. Translational research was started at Shinshu University from Oct.30, 2008, at Nagoya University from Nov.11, 2009, and Tobata Kyouritu Hospital from Feb.8, 2010.

  • Research Products

    (8 results)

All 2010 2009 2008 2007 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (2 results) Book (1 results) Remarks (1 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Anti-cancer effect of hyperthermia on breast cancer by magnetite nanoparticle-loaded anti-HER2 immunoliposomes2009

    • Author(s)
      T. Kikumori, T. Kobayashi, M. Sawaki, T. Imai
    • Journal Title

      Breast Cancer Research Treatment 113

      Pages: 435-441

    • Peer Reviewed
  • [Journal Article] Intracellular hyperthermia using magnetic nanoparticles : A novel method for hyperthermia clinical applications2008

    • Author(s)
      A. Ito, T. Kobayashi
    • Journal Title

      Thermal Medicine 24

      Pages: 113-129

    • Peer Reviewed
  • [Presentation] メラノーマに対する温熱療法と樹状細胞の併用療法の効果2008

    • Author(s)
      小林猛
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
  • [Presentation] 温熱治療におけるmatrix metalloproteinase-3 (MMP-3)阻害剤の細胞死滅促進効果2007

    • Author(s)
      小林猛、西村奈津実、奥田和智、尾藤宗俊
    • Organizer
      日本ハイパーサーミア学会第24回大会
    • Place of Presentation
      前橋
    • Year and Date
      2007-09-14
  • [Book] ナノ粒子・マイクロ粒子の調製と応用技術(川口春馬監修)(磁性ナノ粒子を用いた新しいがん治療法の開発)2010

    • Author(s)
      小林猛、井藤彰、本多裕之
    • Total Pages
      197-209
    • Publisher
      シーエムシー出版
  • [Remarks] その他関連した成果 中日新聞記事、2007年10月30日

    • URL

      http://stu.isc.chubu.ac.jp/bio/public/Bio_Chem/labo/kobayashi_lab/index.html

  • [Patent(Industrial Property Rights)] 細胞培養方法及び培養組織2009

    • Inventor(s)
      井藤彰、本多裕之、小林猛、上田実、各務秀明、畠賢一郎
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Number
      特許,特許第4322253号
    • Acquisition Date
      2009-06-12
  • [Patent(Industrial Property Rights)] 細胞培養方法2008

    • Inventor(s)
      井藤彰、本多裕之、小林猛、上田実、各務秀明、畠賢一郎
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Number
      特許,特許第4160842号
    • Acquisition Date
      2008-07-25

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Published: 2011-06-18   Modified: 2016-04-21  

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