2009 Fiscal Year Final Research Report
Regulatory mechanism of breakdown and reconstruction of reproductive organs
| Project/Area Number |
19370025
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Morphology/Structure
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| Research Institution | Okayama University |
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Principal Investigator |
TAKAHASHI Sumio Okayama University, 大学院・自然科学研究科, 教授 (90144807)
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| Co-Investigator(Renkei-kenkyūsha) |
TAKEUCHI Sakae 岡山大学, 大学院・自然科学研究科, 准教授 (20226989)
FUKAMACHI Hiroshi 東京医科歯科大学, 大学院・医歯学総合研究科, 講師 (70134450)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 細胞増殖 / アポトーシス / 成長因子 / 下垂体 / 卵巣 / 子宮 / 遺伝子発現 / マウス |
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| Research Abstract |
Proliferation, differentiation and apoptosis (programmed cell-death) are regulated by signaling molecules secreted from cells, hormones, growth factors and cytokines, and by extracellular matrices surrounding cells. The present study was aimed at studying regulatory mechanism of the proliferation and apoptosis in the mouse pituitary and uterus. We showed regulatory mechanisms of gene expression of growth factors and hormones that were associated with proliferation in the pituitary and uterus, and also factors which modified actions of growth factors and hormones.
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[Journal Article] Identification of unique thyrotropin receptor (TSHR) splice variants in the chicken: The chicken TSHR gene revisited2008
Author(s)
Grommen, S.V., Taniuchi, S., Darras, V.M., S Takahashi, Takeuchi, S., Groef, B.D.
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Journal Title
Gen Comp Endocrinol 156
Pages: 460-463
Peer Reviewed
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[Journal Article] Loss of Runx3 affects ovulation and estrogen-induced endometrial cell proliferation in female mice.2008
Author(s)
Sakuma, A., Fukamachi, H., Ito, K., Ito, Y., Takeuchi, S., Takahashi, S.
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Journal Title
Molec. Reprod. Dev. 75
Pages: 1653-1661
Peer Reviewed
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[Journal Article] Expression of interleukin-18 receptor mRNA in the mouse endometrium.2007
Author(s)
Otsuki, M., Kusumoto, K., Murakami, Y., Kanayama, M., Takeuchi, S., Takahashi, S.
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Journal Title
J. Reprod. Dev. 53
Pages: 59-68
Peer Reviewed
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[Journal Article] Estrogen-dependent expression of the tissue kallikrein gene (Klk1) in the mouse uterus and its implications for endometrial tissue growth.2007
Author(s)
Rajapakse, S., Yamano, N., Ogiwara, K., Hirata, K., Takahashi, S., Takahashi, T.
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Journal Title
Molec. Reprod. Dev. 74
Pages: 1053-1063
Peer Reviewed
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[Journal Article] Alternative leader exon usage in mouse IGF-I mRNA variants: class 1 and class 2 IGF-I mRNAs.2007
Author(s)
Ohtsuki, T., Otsuki, M., Murakami, Y., Hirata, K., Takeuchi, S., Takahashi, S.
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Journal Title
Zool. Sci. 24
Pages: 241-247
Peer Reviewed
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[Presentation] Transfroming growth factor-αregulates insulin-like growth factor binding protein-3 gene expression in the mouse endometrial stromal cells.2010
Author(s)
Takahashi, S., Maekawa, T., Sakuma, A., Taniuchi, S., Kanayama, M., Iguchi, T., Takeuchi, S.
Organizer
14th International Congress of Endocrinology
Place of Presentation
Kyoto
Year and Date
2010-03-27
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[Presentation] Decreased expression of IGF1 and TGFαmRNAs in the uterus of streptozotocin- induced diabetic mice.2010
Author(s)
Tochigi, M., Manabe, Y., Moriwaki, A., Kanayama, M., Takeuchi, S., Takahashi, S.
Organizer
14th International Congress of Endocrinology
Place of Presentation
Kyoto
Year and Date
2010-03-27
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[Presentation] Loss of Runx3 affects ovulation and estrogen-induced endometrial cell proliferation in female mice.2008
Author(s)
Takahashi, S., Sakuma, A., Fukamachi, H., Ito, K., Ito, Y., S. Takeuchi, S.
Organizer
The Endocrine Society, 90th Annual Meeting, Program & Abstracts
Place of Presentation
San Francisco
Year and Date
2008-06-16
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