2009 Fiscal Year Final Research Report
High-performance glucose-sensitive nanocapsules
| Project/Area Number |
19390010
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Physical pharmacy
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| Research Institution | Tohoku University |
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Principal Investigator |
ANZAI Jun-ichi Tohoku University, 大学院・薬学研究科, 教授 (40159520)
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| Co-Investigator(Kenkyū-buntansha) |
SATO Katsuhiko 東北大学, 大学院・薬学研究科, 助教 (80400266)
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| Project Period (FY) |
2007 – 2009
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| Keywords | グルコース / ナノカプセル |
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| Research Abstract |
The development of nanocapsules for glucose determination and for release insulin in response to enhanced glucose level have been studied. CaCO_3 nanoparticles containing lectin complexes or insulin were coated with polyelectrolyte thin films followed by dissolution of the nanoparticle, resulting in nanocapsules. The nanocapsules thus prepared were successfully used for glucose determination and for insulin release in response to enhanced glucose level.
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