2009 Fiscal Year Final Research Report
The effect of ageing on the adult stem cells of tongue and masticatory muscles
| Project/Area Number |
19390501
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
補綴理工系歯学
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| Research Institution | Tsurumi University |
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Principal Investigator |
MORITO Mitsuhiko Tsurumi University, 歯学部, 教授 (30089429)
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| Co-Investigator(Kenkyū-buntansha) |
YAMANE Akira 鶴見大学, 歯学部, 教授 (20166763)
FUKUI Tadayoshi 鶴見大学, 歯学部, 助教 (10267544)
SUGA Takeo 鶴見大学, 歯学部, 助教 (40247333)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 成体幹細胞 / 骨格筋 / インスリン様増殖因子 / マイオスタチン / トリグリセロール |
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| Research Abstract |
The present results suggest that the extent of skeletal muscle atrophy is associated with activity of adult stem cells through IGFR1, myostatin down-regulate the velocity of differentiation of skeletal muscle cell lineage via activity of adult stem cell and the influence of triglycerol on the activity, proliferation and differentiation of adult stem cells is limited.
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[Journal Article] Effects of clenbuterol, aβ_2-adrenergic agonist, on sizes of masseter, temporalis, digastric, and tongue muscles2009
Author(s)
ISHIKAWA, C., OGAWA, T., IKAWA, T., YAMANE, A.
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Journal Title
Open Dent. J 3
Pages: 191-196
Peer Reviewed
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[Journal Article] Extracellular matrix-mediated tissue remodeling following axial movement of teeth2007
Author(s)
LUAN, X., ITO, Y., HOLLIDAY, S., WALKER, C., DANIELL, J., GALANG, T.M., FUKUI, T. YAMANE, A., BEGOLE, E., EVANS, C., DIEKWISCH, T.G.H
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Journal Title
J. Histochem. Cytochem 55(2)
Pages: 127-140
Peer Reviewed
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[Journal Article] BMP2, BMP4, and their receptors are expressed in the differentiating muscle tissues of mouse embryonic tongue2007
Author(s)
SUGA, T., FUKUI, T., SHINOHARA, A., LUAN, X., DIEKWISCH, T.G.H., MORITO, M., YAMANE, A
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Journal Title
Cell Tissue Res 329(1)
Pages: 103-117
Peer Reviewed
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[Journal Article] Effect of third molar absence on development of masticatory muscles in EL mice
Author(s)
NARIYAMA, M., KOTA, Y., TASHIMA, I., TOMOHIRO, T., YAMANE, A., ASADA, Y.
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Journal Title
Pediatric Dent. J (In press)
Peer Reviewed
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[Journal Article] BMP-2 Regulates the Formation of Oral Sulcus in Mouse Tongue by Altering the Balance between TIMP-1 and MMP-13
Author(s)
FUKUI, T., SUGA, T., IIDA, R., MORITO, M., LUAN, X., DIEKWISCH, T.G.H., NAKAMURA, Y., YAMANE, A.
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Journal Title
Peer Reviewed
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