2009 Fiscal Year Final Research Report
Chemical Biology of Golgi Membrane Dynamics
| Project/Area Number |
19580098
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Hosei University |
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Principal Investigator |
TAKATSUKI Akira Hosei University, 生命科学部, 教授 (80011972)
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| Project Period (FY) |
2007 – 2009
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| Keywords | ゴルジ / 抗生物質 / ケミカルバイオロジー / 中心体 / 微小管 / 膜ダイナミクス |
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| Research Abstract |
The Golgi maintains its characteristic structure by a dynamic equilibrium manner, but this mechanism remains to be clarified. Chemicals affecting Golgi membrane dynamics were found at a relatively high ratio among those known to affect transition to mitotic phase of cell cycle and induce apoptosis. Results indicating that they act on the centrosome suggest that the centrosome plays important roles in the control of Golgi membrane dynamics.
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