2009 Fiscal Year Final Research Report
The diagnosis of acute myeloid leukemia based on the new WHO classification in the multicenter study.
| Project/Area Number |
19590565
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Laboratory medicine
|
|---|
| Research Institution | University of the Ryukyus |
|---|
Principal Investigator |
KURIYAMA Kazutaka University of the Ryukyus, 医学部, 教授 (90128174)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
MIYAZAKI Yasushi 長崎大学, 医学部・歯学部附属病院, 講師 (40304943)
HATA Tomoko 長崎大学, 医学部・歯学部附属病院, 助教 (10346968)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Keywords | 急性骨髄性白血病 / WHO分類 / 中央診断システム / 染色体異常 / 遺伝子異常 / 予後因子 |
|---|
| Research Abstract |
We diagnosed the patients registered with AML treatment protocol (AML-97) of Japan Adult Leukemia Study Group according to WHO classification in 2001.628 patients registered with the AML-97 protocol were diagnosed as AML with recurrent genetic abonrmalities (171patients;26.8%), AML with multilineage dysplasia (133;20.8%), AML not otherwise categorized (331;51.9%) or acute leukemia of ambiguous lineage (3;0.5%), respectively. These diagnoses were not so different from the diagnoses by the revised WHO classification in 2008, except that 32 patients having 11q23 abnormalities decreased to 9 patients because only t(9;11) was taken up in 2008.
|
