2009 Fiscal Year Final Research Report
Molecular genetic study of intracellular signal transduction in suicide
| Project/Area Number |
19591354
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Kobe University |
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Principal Investigator |
NISHIGUCHI Naoki Kobe University, 大学院・医学研究科, 医学研究員 (10362774)
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| Co-Investigator(Kenkyū-buntansha) |
SHIRAKAWA Osamu 近畿大学, 医学部, 教授 (40243307)
UENO Yasuhiro 神戸大学, 大学院・医学研究科, 教授 (30184956)
MAEDA Kiyoshi 神戸大学, 大学院・医学研究科, 教授 (80116251)
FUKUTAKE Masaaki 神戸大学, 大学院・医学研究科, 助教 (80457085)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 精神薬理学 / 神経科学 |
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| Research Abstract |
Candidate genes which are thought to be biologically involved in suicidal behaviour were examined for association with suicide. For example, regulator of G protein signaling 2 (RGS2) gene was associated with suicide using its polymorphisms, and the level of RGS2 protein was altered in suicidal postmortem brains. Additionally, we reported the results of other genetic association studies and screening examination with microarray in suicide.
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[Presentation] Neurobiology of suicide2009
Author(s)
K. Maeda, O. Shirakawa, N. Nishiguchi
Organizer
The Kobe Conference of the International Neuropsychiatric Association
Place of Presentation
Kobe International Convention Center, Kobe, Japan
Year and Date
20090912-20090913
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