Basic research of a novel dental material : Calcium Titanium Oxide-Amorphous Carbon for applying the lining material

2009 Fiscal Year Final Research Report

• Project/Area Number: 19592236
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: 補綴理工系歯学
• Research Institution: Okayama University
• Principal Investigator: TAKAGI Yoru Okayama University, 大学院・医歯薬学総合研究科, 非常勤講師 (20124696)
• Co-Investigator(Kenkyū-buntansha): NAGAI Noriyuki 岡山大学, 名誉教授 (90085770) ; NAGATSUKA Hitoshi 岡山大学, 大学院・医歯薬学総合研究科, 教授 (70237535) ; SUZUKI Kazuomi 岡山大学, 大学院・医歯薬学総合研究科, 教授 (30050058) ; YAMAMOTO Toshio 岡山大学, 大学院・医歯薬学総合研究科, 教授 (30107776) ; IRIE Masao 岡山大学, 大学院・医歯薬学総合研究科, 助教 (90105594) ; TSUJIGIWA Hidetsugu 岡山大学, 大学院・医歯薬学総合研究科, 助教 (70335628)
• Project Period (FY): 2007 – 2009
• Keywords: 歯科材料 / 生体材料 / チタン酸カルシウム / ナノ粒子 / 裏装材

Research Abstract

We have developed modified thermal decomposition method to obtained "calcium titanium oxide-amorphous carbon" (CaTiO3-aC). The purpose of the research was to evaluate the effect of this material as nanoparticles for applying the dental material. We analyzed the chemical composition of the particles and studied it's influence on the cell. Our results suggest that CaTiO3-aC plays a dominant effect on cell response, which could be considered as an important biomaterial for not only dental materials but also medical and industrial materisls.

Research Products

• [Journal Article] Effect of Fluoride-substituted Apatite on In Vivo Bone Formation. (2010)
  • Author(s): Inoue M, Rodriguez AP, Nagai N, Nagatsuka H, Legeros RZ, Tsujigiwa H, Inoue M, Kishimoto E, Takagi S
  • Journal Title: J Biomater Appl (Epub ahead of print)
  • Peer Reviewed
• [Journal Article] Influence of the microenvironment on gene and protein expression of odontogenicand osteogenic-like cells. (2009)
  • Author(s): Rodriguez AP, Tsujigiwa H, Gunduz M, Cengiz B, Nagai N, Tamamura R, Borkosky SS, Takagi T, Inoue M, Nagatsuka H
  • Journal Title: Biocell 33 Pages: 39-47
  • Peer Reviewed
• [Journal Article] Development of New Titanium CoatinMaterial (CaTiO3-aC) with Modified TDecomposition Method (2008)
  • Author(s): Nagai N, Okauchi M, Rodriguez A, Gunduz M, Hu H, Kubota M, Nagaoka N, Inoue M, Nagatsuka H, Takagi T, Akao M
  • Journal Title: Journal of Hard Tissue Biology 17 Pages: 47-54
  • Peer Reviewed
• [Journal Article] Chemical Analysis of a NoveCoating Material, CaTiO3-aC. (2008)
  • Author(s): Okauchi-Yabuuchi M, Tamamura R, Nagaoka N, Takagi S, Kishimoto E, Takagi T, Rodriguez A, Inoue M, Nagatsuka H, Akao M, Nagai N
  • Journal Title: Journal of Hard Tissue Biology 17 Pages: 115-120
  • Peer Reviewed
• [Presentation] 新規生体材料チタン酸カルシウム-炭酸カルシウム(CaTiO3-CaCO3)の細胞学的検討 (2009)
  • Author(s): 井上美穂
  • Organizer: 第51回歯科基礎医学会学術大会・総会
  • Place of Presentation: 新潟
  • Year and Date: 2009-09-11
• [Presentation] 新規コーティング材CaTiO3-aCの組織学的検討 (2009)
  • Author(s): 玉村亮
  • Organizer: 第18回硬組織再生生物学会総会・学術大会
  • Place of Presentation: 札幌
  • Year and Date: 2009-09-05
• [Presentation] Effect of CaTiO3-C coating by thermal decomposition method on osteoblastic cell response (2008)
  • Author(s): M. Inoue
  • Organizer: The 4th International Symposium on Apatite and Correlative Biomaterials
  • Place of Presentation: フィリピン
  • Year and Date: 2008-09-12
• [Presentation] 新規生体材料(チタン酸カルシウム-非晶質炭素複合物CaTiO3-aC)の細胞学的検討 (2008)
  • Author(s): 松田寛之
  • Organizer: 第17回硬組織再生生物学会学術大会・総会
  • Place of Presentation: 徳島
  • Year and Date: 2008-08-30