2009 Fiscal Year Final Research Report
Pathobiological Analysis of Odontogenic Tumors and Development of Local Injection Therapy
| Project/Area Number |
19592341
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Surgical dentistry
|
|---|
| Research Institution | Kyushu University |
|---|
Principal Investigator |
NINOMIYA Tomohiro Kyushu University, 歯学研究院, 助教 (10346801)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
KUBOTA Yasutaka 九州大学, 大学病院, 講師 (60205151)
SHIRASUNA Kanemitsu 九州大学, 歯学研究院, 教授 (30093420)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Keywords | 歯学 / 歯原性腫瘍 / 角化嚢胞 |
|---|
| Research Abstract |
The purpose of this study is to analyze odontogenic tumors pathobiologically and then, we try to develop the new therapy with local injection. In our study suggested that Interleukin-1α (IL-1α) play a crucial role in the growth of keratocystic odontogenic tumors (KCOTs). Now, we try to make an antisense of IL-1α for the new therapy with local injection.
|
