2009 Fiscal Year Final Research Report
Genetic reconstitution of autoimmune diseases in mice.
| Project/Area Number |
19689012
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Immunology
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| Research Institution | The University of Tokushima |
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Principal Investigator |
OKAZAKI Taku 徳島大学, 疾患ゲノム研究センター, 教授 (00362468)
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| Project Period (FY) |
2007 – 2009
|
| Keywords | 遺伝子 / 細胞 / 実験動物 / 自己免疫疾患 / 連鎖解析 / I型糖尿病 |
|---|
| Outline of Final Research Achievements |
We have identified several autoimmune susceptible loci by genetic linkage analyses on animal models of type I diabetes, peripheral neuropathy, and myocarditis. We have also succeeded in reconstituting type I diabetes on the disease-resistant strain by introducing diabetes susceptible loci.
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| Free Research Field |
医歯薬学
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