2009 Fiscal Year Final Research Report
Effect of Oral Cryotherapy for Preventing Stomatitis, Adverse Chemotherapy
| Project/Area Number |
19890178
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Clinical nursing
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| Research Institution | Yamanashi Prefectural University |
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Principal Investigator |
TAKAGISHI Hiromi Yamanashi Prefectural University, 看護学部, 助教 (10453052)
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| Project Period (FY) |
2008 – 2009
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| Keywords | がん / 化学療法 / 口内炎 / クライオセラピー |
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| Research Abstract |
Objective : To clarify the effect of oral cryotherapy on the development of stomatitis in the cancer patient who treatment with chemotherapy. Methods : Using a randomized crossover design. Patients (the malignant lymphoma patients during a chemotherapy) were randomized to the cryotherapy group or the control group. Subjects evaluate their QOL utilizing the SF-36 QOL scale. The physician evaluates subject stomatitis both before and 14 days after the initiation of chemotherapy, utilizing the NCI-CTC [National Cancer Institute-Common Toxicity Criteria] Grade Scale. Results : There was no difference in the development of stomatitis between the cryotherapy group and the control group. There was a decrease in QOL between the second and third cycles of chemotherapy as measured by the SF36 QOL scale. Conclusion : The low incidence of stomatitis in subjects during both the cryotherapy group and control group may be due to inadequate consideration of the post-chemotherapy schedule of cryotherapy.
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Research Products
(5 results)
