Development of Innovative Chiral Molecules and Polymers Analysis and Separation Methods Based on Three-Dimensional Space Imaging

2022 Fiscal Year Final Research Report

• Project/Area Number: 19H00909
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Review Section: Medium-sized Section 35:Polymers, organic materials, and related fields
• Research Institution: Kyoto University
• Principal Investigator: Ogoshi Tomoki 京都大学, 工学研究科, 教授 (00447682)
• Co-Investigator(Kenkyū-buntansha): 淺川 雅 金沢大学, ナノマテリアル研究所, 准教授 (90509605)
• Project Period (FY): 2019-04-01 – 2023-03-31
• Keywords: ピラーアレーン / 超分子構造 / 直接観察 / 面性不斉 / ゾル－ゲル転移 / キラル増幅

Outline of Final Research Achievements

The planar chirality of pillar[5]arene can be controlled by external conditions, but it was difficult to completely bias the chirality toward the S- and R-forms. Therefore, molecular design and synthesis of homochiral pillar[5]arenes with fully fixed planar chirality were performed in this study. A click reaction-based functional group introduction method was also developed to allow the introduction of various substituents. We also visualized assemblies of the obtained homochiral pillar[5]arenes at the molecular level, and evaluated the effects of the higher-order structures on physical properties such as optical properties, chiral amplification, and sol-gel transitions.

Free Research Field

超分子化学・高分子化学

Academic Significance and Societal Importance of the Research Achievements

高分子・超分子は、構成単位が同じであっても、その取りうる高次構造が異なることで、全く異なる性質を示す。例えば単純なポリスチレンの様な一般的な汎用性高分子であっても、その高次構造によって融点や強度などの物性が全く異なる。本研究では、面不斉（S体とR体）が偏った柱型環状分子ピラーアレーンが繋がった超分子構造について明確に観察することで、真に超分子の高次構造が及ぼす、光学特性・キラル増幅・ゾル―ゲル転移といった物性との相関を明らかにすることができた。