Establishment of bacteriological examination method for diagnosing healing endodontic periodontal lesions

2021 Fiscal Year Final Research Report

• Project/Area Number: 19K10124
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 57030:Conservative dentistry-related
• Research Institution: Tokyo Medical and Dental University
• Principal Investigator: Kobayashi Hiroaki 東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師 (50396967)
• Co-Investigator(Kenkyū-buntansha): 川島 伸之 東京医科歯科大学, 大学院医歯学総合研究科, 講師 (60272605) ; 竹内 康雄 東京医科歯科大学, 大学院医歯学総合研究科, 講師 (60396968) ; 片桐 さやか 東京医科歯科大学, 歯学部附属病院, 准教授(キャリアアップ) (60510352) ; 須藤 毅顕 東京医科歯科大学, 統合教育機構, 特任助教 (10821168) ; 青木 章 東京医科歯科大学, 大学院医歯学総合研究科, 教授 (30302889)
• Project Period (FY): 2019-04-01 – 2022-03-31
• Keywords: 歯内歯周病変

Outline of Final Research Achievements

Endoperio lesions are diseases in which periodontal pockets and apical lesions are in communication. Clinically, endoperio lesions caused by end lesions are easy to heal, and lesions that develop from periodontitis are difficult to heal. However, it is difficult to determine endoperio lesions caused by end lesions preoperatively. In this study, preoperative periodontal pocket bacteria were examined. As a result, endoperio lesions, which have a large amount of periodontal disease-derived bacteria in the periodontal pocket of the lesion before surgery, tend to be "difficult to heal." Because there are many endo-derived bacteria in the endoperio lesion that has spread from the endo lesion, it was suggested that bacterial tests could predict healing endoperio lesions.

Free Research Field

歯周治療学

Academic Significance and Societal Importance of the Research Achievements

根管治療で治癒するエンドペリオ病変を術前検査により判別できるようになれば、治療前にその病態にあった適切な治療方法が選択でき、いままでは治らないものと思われていた「エンドペリオ病変」の中で治癒しやすいものを判断できるようになり、安易な抜歯や、不要な歯周治療を防ぐことが可能となる。