2021 Fiscal Year Research-status Report
Fabrication of bioactive zirconia implant
| Project/Area Number |
19K10250
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| Research Institution | Nagasaki University |
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Principal Investigator |
バラネザハド アリレザ 長崎大学, 医歯薬学総合研究科(歯学系), 助教 (00608870)
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| Co-Investigator(Kenkyū-buntansha) |
渡邊 郁哉 長崎大学, 医歯薬学総合研究科(歯学系), 教授 (00274671)
尾立 哲郎 長崎大学, 病院(歯学系), 講師 (70513167)
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| Project Period (FY) |
2019-04-01 – 2023-03-31
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| Keywords | Implant / Zirconia / Bioactivity |
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| Outline of Annual Research Achievements |
Ceramic 45S5 BG (45%SiO2, 24.5%Na2O, 24.5%CaO, and 6%P2O5 by weight) have gained researchers attention as a functional biomaterial due to its bioactive surface and osseointegration ability. It has been approved that BG 45S5 can heal and repair bone damages. Therefore, The sol-gel technique preparation protocol followed to prepare 45S5 BG, by mixing the tetraethylorthosilicate (TEOS, Wako, Tokyo, Japan), nitric acid, triethylphosphate (TEP, Wako, Japan), calcium nitrate tetrahydrate (Wako), sodium nitrate (Wako). The zirconia substrates coated by one-time vacuum sol-dipping method under 0.1 bar pressure dipped for 60 s and dried at 60°C for 1 hour followed by sintering at 1200°C for 1 hour to melt the BG on the surface in a programmable furnace with a heating rate of 10°C/min. The characterizations such as morphology, adhesion test and roughness investigated after BG coating. The SEM images confirmed that 900°C is not enough to melt and cover entire surface therefore 1200°C was applied. Also the Fractography result showed that the thickness of the coating layer is controllable between 5 um to 45 um. The XRD result mentioned the non-crystallin and crystalline BG phase structures.
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| Current Status of Research Progress |
Current Status of Research Progress
3: Progress in research has been slightly delayed.
Reason
The BG coating was fully covered the zirconia substrate also the BG coating firmly adhered to the surface and the thickness of coating was controllable. Therefore,
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| Strategy for Future Research Activity |
The BG coating, prepared by sol-gel technique, on the rough bead-fused zirconia substrates coated by one-time vacuum sol-dipping method under 0.1 bar pressure and dipped for 60s and sintered at 1200°C for 1 hour will be characterized more. The characterizations such as TEM and adhesion test and roughness will be investigated. Later cell study will be investigated for biological properties.
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| Causes of Carryover |
学会中止などで旅費の執行ができなかったため、次年度使用額が生じた。繰り越し金は物品費、人件費、謝金に使用する計画である。
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