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2022 Fiscal Year Final Research Report

Oral function utilization for sarcopenia diagnosis of very elderly people

Research Project

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Project/Area Number 19K10254
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 57050:Prosthodontics-related
Research InstitutionNihon University

Principal Investigator

IINUMA Toshimitsu  日本大学, 歯学部, 教授 (10246902)

Co-Investigator(Kenkyū-buntansha) 伊藤 智加  日本大学, 歯学部, 講師 (40459912)
西尾 健介  日本大学, 歯学部, 助教 (50780558)
網干 博文  日本大学, 歯学部, 特任教授 (60212560)
Project Period (FY) 2019-04-01 – 2023-03-31
Keywords高齢者 / 口腔機能 / フレイル / オーラルフレイル / 疫学調査
Outline of Final Research Achievements

In this study, in cooperation with the Nihon University School of Dentistry Alumni Association, we investigated the oral function and physical functions of 250 very elderly people aged 80 who lived over in eight regions in Japan. (Tokyo, Saitama, Kanagawa, Okinawa, Niigata, Nagano, Hiroshima and Aomori) Results showed that subjects diagnosed with oral hypofunction had statistically significantly lower physical function and were at higher risk for frailty.
Furthermore, with regard to cognitive function, a clear decline in cognitive function was observed in the subject group judged to have oral hypofunction. These findings suggest that prevention of oral frailty may affect cognitive function. From the above, it became clear that maintenance of oral function in the very elderly period may contribute to extension of healthy life expectancy.

Free Research Field

高齢者歯科学

Academic Significance and Societal Importance of the Research Achievements

超高齢者における口腔機能や身体的健康度の向上には、的確な状態把握が最重要項目と考える。事実、口腔機能の低下とオーラルフレイルとには密接な関連性があるため、現在、様々な口腔機能に関する検査が行われている。しかし、これまで80歳以上の超高齢者を対象に口腔機能の変化から全身の健康状態の変化をとらえようとした研究は少ない。
そこで本研究は、「80歳以上の超高齢者の最大咬合力等の口腔機能の低下は、ロコモティブ・シンドロームの早期発見に活用できる。」との仮説を立て、超高齢者の口腔機能と握力を指標とし、身体機能の違いがサルコぺニアや認知機能等に及ぼす影響を検討し両者に関連性があることを示した。

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Published: 2024-01-30  

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