2021 Fiscal Year Final Research Report

Analysis of Herpes zoster by birth in Japanese females and setting of life planning.

Research Project

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Project/Area Number	19K10966
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Review Section	Basic Section 58060:Clinical nursing-related
Research Institution	Senri Kinran University
Principal Investigator	TANAKA KEIKO 千里金蘭大学, 看護学部, 教授 (30290357)
Co-Investigator(Kenkyū-buntansha)	市川きみえ清泉女学院大学, 看護学部, 准教授 (10609142) 生駒妙香千里金蘭大学, 看護学部, 講師 (30785225) 白木公康千里金蘭大学, 看護学部, 教授 (50135745) 石田美佳子千里金蘭大学, 看護学部, 助教 (60825694) 藤野百合千里金蘭大学, 看護学部, 准教授 (70759307) 寺本久美子千里金蘭大学, 看護学部, 助教 (80837542)
Project Period (FY)	2019-04-01 – 2022-03-31
Keywords	帯状疱疹 / ウイルス / ワクチン / 女性 / ライフイベント / 出産 / 授乳
Outline of Final Research Achievements	In the Miyazaki Study, a large-scale epidemiological study of herpes zoster, we analyzed the dermatomes of onset of herpes zoster by age/sex. The incidence in women who were 50 years of age or older was significantly higher than that in men, and herpes zoster in women was consistent with areas for childbirth and breastfeeding. We also examined the degree of awareness of herpes zoster in middle-aged and elderly women. The research on the awareness about herpes zoster among middle-aged and older women revealed that this subset of women is insufficiently aware of the disease and of the available preventive vaccines, indicating the need for public education. We developed a booklet titled “Herpes zoster Prevention Guidebook - Toward Healthy Middle and Senior Women” and examined its effectiveness. Once peri-and post-menopausal women aged 50 or older become vaccinated against herpes zoster, the epidemiologic trends of herpes zoster may also change.
Free Research Field	看護学
Academic Significance and Societal Importance of the Research Achievements	女性は出産・授乳後20年間の潜伏期を経て、出産時の陣痛や分娩の際に関わる領域（産科麻酔）と授乳に関連する領域に帯状疱疹が発症しやすく、女性特有のライフイベントが関与している。本研究の結果は、出産や授乳を行った女性への早期発見・早期治療、帯状疱疹予防ワクチンを受けることに関する啓発を行うことができる。 50歳代以降の女性が適切な時期にワクチン接種を行うことで帯状疱疹を発症・重症化するリスクを減らし、帯状疱疹後遺症への移行の防止につながることか期待される。