Analysis of the microbiome in the ear canals of dogs with and without otitis externa

2020 Fiscal Year Final Research Report

• Project/Area Number: 19K16011
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 42020:Veterinary medical science-related
• Research Institution: Anicom Specialty Medical Institute Inc
• Principal Investigator: Shima Ayaka アニコム先進医療研究所株式会社(研究開発課), 研究開発課, 研究員 (00813859)
• Project Period (FY): 2019-04-01 – 2021-03-31
• Keywords: 外耳炎 / 細菌叢 / イヌ

Outline of Final Research Achievements

Otitis externa is a common disease in dogs. However, the association between bacteria and the development of otitis externa has not been elucidated. In this study, the association between otitis externa and the skin microbiota in the ear canal was evaluated by comparing the microbiota in dogs with and without otitis externa.
The microbiota in the ear canal differed between dogs with and without otitis externa. Moreover, the microbiome of healthy ear were different from that of diseased one in same individual with unilateral otitis externa. It differed to that of dogs without otitis externa.These results suggest that the microbiota in ear canal are associated with otitis externa and it might be predisposing factor of otitis externa.

Free Research Field

獣医学

Academic Significance and Societal Importance of the Research Achievements

本研究から、外耳炎と外耳道細菌叢には関連がある事が示唆され、外耳炎を発症しやすい細菌叢が存在する可能性があると考えられた。本成果は、腸内細菌叢をターゲットとした外耳炎の新規治療法、および予防法の開発の一助となると考えられる。