Reliability evaluation test of Hyperemic Absolute coronary flow

2021 Fiscal Year Final Research Report

• Project/Area Number: 19K17590
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 53020:Cardiology-related
• Research Institution: Hamamatsu University School of Medicine
• Principal Investigator: mogi satoshi 浜松医科大学, 医学部附属病院, 診療助教 (60573368)
• Project Period (FY): 2019-04-01 – 2022-03-31
• Keywords: 冠微小循環

Outline of Final Research Achievements

Although coronary microcirculatory disorders have been recognized, a test system that can perform accurate evaluation has not been established. Recently, it has become possible to measure them by using a special catheter approved in Europe and the United States, but its use in Japan has not been approved. Therefore, it was evaluated whether similar measurement is possible by using a catheter currently approved in Japan. After the measurement by the original method using pigs, the measurement was performed with the catheter used in Japan. It was found that measurement is possible even with catheters used in Japan.

Free Research Field

冠循環

Academic Significance and Societal Importance of the Research Achievements

本邦で認可されている冠動脈用カテーテルにおいても原法と同じカテーテルと同様に冠血流、微小血管抵抗が計測が可能であることが分かった。心不全や心筋症、弁膜症の微小循環障害を評価できる検査系が確立できれば病態解明が進むものと思われる。