Computational Fluid Dynamic Analysis of Cerebral Aneurysms Considering Vessel Wall Elasticity

2022 Fiscal Year Final Research Report

• Project/Area Number: 19K18411
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 56010:Neurosurgery-related
• Research Institution: National Hospital Organization, Kyushu Medical Center (Clinical Institute)
• Principal Investigator: Matsuo Satoshi 独立行政法人国立病院機構九州医療センター(臨床研究センター), その他部局等, 脳神経外科 客員臨床研究員 (80734938)
• Project Period (FY): 2019-04-01 – 2023-03-31
• Keywords: cerebral aneurysm / CFD / ECG gated head CTA

Outline of Final Research Achievements

We analyzed the morphological changes of cerebral aneurysms between cardiac cycles and compared them between two groups by aneurysm size (>5 mm and <5 mm) and by site of origin, with the aim of separating groups with high and low rupture rates, using data from UCAS Japan. The results showed that in the two groups divided by the site of aneurysm occurrence, the group considered to be at high risk of rupture had a significantly greater rate of change in aneurysm neck diameter between cardiac cycles.

Free Research Field

脳神経外科

Academic Significance and Societal Importance of the Research Achievements

破裂riskが高いと思われる部位の脳動脈瘤は動脈瘤頚部径の心周期間での変化率が有意に大きいことが判明した。これは、破裂riskが低いと思われている部位や大きさの動脈瘤の中から破裂riskが高い動脈瘤を抽出する際の一助になる可能性があると考えられた。