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2021 Fiscal Year Final Research Report

Biomechanical analysis of Centralization technique for meniscus extrusion using porcine knees

Research Project

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Project/Area Number 19K18524
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 56020:Orthopedics-related
Research InstitutionTokyo Medical and Dental University

Principal Investigator

Kohno Yuji  東京医科歯科大学, 統合研究機構, 非常勤講師 (10822562)

Project Period (FY) 2019-04-01 – 2022-03-31
Keywords半月板 / バイオメカニクス / Centralization法
Outline of Final Research Achievements

Our clinical group developed the "Centralization technique" as a treatment for "meniscus extrusion". Although this surgical technique obtained good postoperative clinical results, the "biomechanics" of meniscal function was not clarified.
In this study, we established a examination method for "meniscal biomechanics" using fresh frozen porcine knees and the original universal tester. Using the established meniscus model and evaluation method, we clarified the effectiveness of the "Centralization technique" in different knee flexion angles. We also clarified the effectiveness of the "centralization technique" with capsular advancement for meniscus extrusion after meniscectomy which was clinically performed.

Free Research Field

整形外科学

Academic Significance and Societal Importance of the Research Achievements

「変形性膝関節症」の原因となる「半月板逸脱」に対する治療法である「Centralization法」に関して、半月板部分切除後の逸脱に対する効果はどうか、深屈曲時の垂直負荷の影響はどうか、などの問いに日常臨床でしばしば直面するが、それらに応える半月板の「バイオメカニクス」は明らかにしていない。本研究では、それらに対する「Centralization法」の有効性を生体力学的側面から解析し明らかにした。本研究成果により「Centralization法」の普及による変形性膝関節症の予防も期待され、臨床上極めて重要である。

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Published: 2023-01-30  

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