Establishing the scientific evidence for a novel bone regeneration procedure using the Er:YAG laser.

2021 Fiscal Year Final Research Report

• Project/Area Number: 19K19066
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 57040:Regenerative dentistry and dental engineering-related
• Research Institution: Tokyo Medical and Dental University
• Principal Investigator: Taniguchi Yoichi 東京医科歯科大学, 歯学部, 非常勤講師 (30648093)
• Project Period (FY): 2019-04-01 – 2022-03-31
• Keywords: 骨再生 / 歯周組織再生治療 / 歯槽堤保存術 / 歯槽堤増大術 / レーザー治療 / 血餅形成

Outline of Final Research Achievements

The study was carried out under the spread of COVID-19, which resulted in a significant delay in the research plan from the initial stage. This made it difficult to use special equipment such as EDX analysers (elemental analysis), which forced some changes in the research plan. As a result of the research, the necessary period for bone graft material to be replaced by bone in the novel bone regeneration procedure currently being performed using lasers was determined. In addition, the appropriate output power for clinical use was determined not only for the Er:YAG laser but also for each of the lasers used in clinical dental practice, and clinically satisfactory results were obtained.
The results of this research have been presented at domestic and international conferences. A case study article is currently being prepared.

Free Research Field

歯周病学

Academic Significance and Societal Importance of the Research Achievements

本研究に用いられた術式は従来法の欠点を補う革新的な術式である。その一方で科学的根拠が不足している点もあり、本研究結果はEr:YAGレーザーを骨再生治療に応用するにあたり、新たな基準として使用することができる。
また、現状歯科臨床ではEr:YAGレーザー以外にも半導体レーザーや炭酸ガスレーザーが多く使用されているため、本研究では前述の3波長のレーザーを用いた場合の適正照射条件を確定させ臨床的に骨再生を確認している。これにより本術式の汎用性が高まり、さらなる骨再生治療におけるレーザーの有用性が期待できる結果と科学的根拠を得ることができた。