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2020 Fiscal Year Final Research Report

The neural analysis between chewing, swallowing and respiration.

Research Project

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Project/Area Number 19K19120
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 57050:Prosthodontics-related
Research InstitutionNiigata University

Principal Investigator

Kouta Nagoya  新潟大学, 医歯学総合病院, 助教 (10806491)

Project Period (FY) 2019-04-01 – 2021-03-31
Keywords嚥下 / 喉頭感覚 / ラット / 筋電図
Outline of Final Research Achievements

We changed the plan of this study due to the technical problem. According to the previous studies, we hypothesized that the presence and degree of the laryngeal sensation changes the swallowing function such as the frequency and the swallowing related muscle activity. However, the physiological effects
of the laryngeal sensation for the swallowing reflex are unknown. So, we analyzed the changing of swallowing by EMG recording with the stimulated frequency and the laryngeal lidocaine anesthesia. The stimulated frequency and the laryngeal lidocaine anesthesia changed the distribution of the swallowing reflex type and the swallowing related muscle activity. Thus, this study suggested that the presence and degree of the laryngeal sensation affected the swallowing function.

Free Research Field

嚥下

Academic Significance and Societal Importance of the Research Achievements

喉頭感覚入力の有無や程度の違いが嚥下関連筋の筋活動を変調させている可能性が示唆された。このことより、喉頭に感覚入力がある状態、例えば、少量の食物を用いる直接訓練を行なっている際などの方が嚥下関連筋をより活動させ、リハビリテーションとして効果的であることが再確認された。ただ単に刺激入力を大きくし、すぐに嚥下反射を誘発させるのではなく、適度な刺激で一定時間刺激を入力した状態で誘発された嚥下反射の方がよりリハビリテーションとしては効果的な可能性があり、今後新たなリハビリテーション方法を模索する上で非常に重要となってくると考えられる。

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Published: 2022-01-27  

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