2021 Fiscal Year Final Research Report
Clarification of swallowing mechanisms by numerical simulation using realistic geometry
| Project/Area Number |
19K20672
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 90110:Biomedical engineering-related
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| Research Institution | Kobe University |
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Principal Investigator |
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| Project Period (FY) |
2019-04-01 – 2022-03-31
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| Keywords | 計算バイオメカニクス / 消化器系バイオメカニクス / 計算力学 / 数値流体力学 / 嚥下 / 嚥下障害 |
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| Outline of Final Research Achievements |
We developed a computational fluid dynamics model of swallowing based on medical imaging. The model showed that the impaired pharyngeal motion causes insufficient pharyngeal pressure, which increases the pharyngeal bolus residue. In addition, the decreased pharyngeal contraction made swallowing of high-viscosity boluses more difficult, suggesting that pharyngeal pressure due to pharyngeal contraction is important for stable swallowing.
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| Free Research Field |
計算生体流体力学
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| Academic Significance and Societal Importance of the Research Achievements |
嚥下機能が低下し，正常な嚥下が困難な状態を「嚥下障害」と呼ぶが，評価・診断指標は主観によるところが大きい．嚥下流動の詳細な様子を観察するのは困難であり，正常な嚥下においてさえどのような力学条件で達成されているのか十分明らかではない．
本研究では，嚥下流動のコンピュータシミュレーション（数値流体力学解析）により，正常な嚥下における力学条件に関する知見を得た．
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