Nano-scale and real-time fluorescence imaging of metal-corrosion reaction dynamics

2020 Fiscal Year Final Research Report

• Project/Area Number: 19K22118
• Research Category: Grant-in-Aid for Challenging Research (Exploratory)
• Allocation Type: Multi-year Fund
• Review Section: Medium-sized Section 28:Nano/micro science and related fields
• Research Institution: Rikkyo University
• Principal Investigator: MORIMOTO Masakazu 立教大学, 理学部, 教授 (70447126)
• Project Period (FY): 2019-06-28 – 2021-03-31
• Keywords: 金属材料 / 腐食 / 蛍光

Outline of Final Research Achievements

In order to create a new method for real-time fluorescence imaging of metal corrosion reaction dynamics with nanometer-scale resolution, we aimed to establish design strategies for fluorescent molecular probes to visualize the spatial distribution of chemical species involved in metal corrosion. By studying the substituent effect on photoresponsive properties of photoswitchable fluorescent diarylethene derivatives, we obtained useful knowledge on control of absorption and fluorescence spectra, improvement of photostability, and proton-responsive functions toward rational design of fluorescent molecular probes.

Free Research Field

有機光化学

Academic Significance and Societal Importance of the Research Achievements

本研究で見出した設計原理に基づくことで、水素イオンのみならず金属イオンに応答する分子を合成することも可能になると考えられる。光と様々な化学種に応答する多重機能性蛍光分子は、微小領域における金属腐食反応や細胞内における化学反応などのダイナミクスをイメージングするための蛍光プローブとして機能し、将来的には金属材料が関わる様々な産業分野や生物学・医学分野などに貢献する可能性を秘めている。