Development of external stimuli responsive chiral chemistry

2020 Fiscal Year Final Research Report

• Project/Area Number: 19K23634
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Multi-year Fund
• Review Section: 0501:Physical chemistry, functional solid state chemistry, organic chemistry, polymers, organic materials, biomolecular chemistry, and related fields
• Research Institution: Yokohama City University
• Principal Investigator: Hattori Shingo 横浜市立大学, 理学部, 助教 (90846726)
• Project Period (FY): 2019-08-30 – 2021-03-31
• Keywords: キラリティ / 外部刺激応答性 / 準安定状態 / 金属錯体 / 高調波光散乱 / 発光

Outline of Final Research Achievements

In this study, we succeeded in in-situ observation of harmonic light scattering signals of porphyrin J-aggregates induced by mechanical rotation for the first time, and clarified the dynamic chiral structure and chiral induction/dissociation mechanism of porphyrin J-aggregates. In addition, we succeeded in synthesizing chiral aggregates of phthalocyanine under mechanical rotation with high reproducibility for the first time, and clarified the chiral induction mechanism of the chiral aggregates composed of the phthalocyanine complex. From these research results, we have obtained new insight for controlling chirality by external stimuli.

Free Research Field

光化学・錯体化学

Academic Significance and Societal Importance of the Research Achievements

本研究成果は、マクロな機械的回転とナノスケールの分子キラリティに結びつけている点から、新しい科学分野となりえるだけでなく、生命のホモキラリティ起源を考える上での手がかりも提供した。さらに、キラル触媒を用いない不斉合成法やキラル光学材料へ調整する方法へと発展することが期待できる。
本研究成果は、Angewandte Chemie International Editionに論文が掲載され、日本経済新聞、Chem-Station等のメディアにて紹介された。