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2010 Fiscal Year Final Research Report

Exposure assessment of polybrominated diphenyl ethers (PBDEs) to human newborns and development of evaluation method

Research Project

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Project/Area Number 20241016
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Risk sciences of radiation/Chemicals
Research InstitutionChiba University

Principal Investigator

MORI CHISATO  Chiba University, 大学院・医学研究院, 教授 (90174375)

Co-Investigator(Kenkyū-buntansha) KOMIYAMA Masatoshi  千葉大学, 大学院・医学研究院, 准教授 (70175339)
TODAKA Emiko  千葉大学, 予防医学センター, 准教授 (30334212)
MATSUNO Yoshiharu  千葉大学, 予防医学センター, 准教授 (00376378)
Project Period (FY) 2008 – 2010
Keywords臭素系難燃剤 / PBDE / PCB / 乳幼児 / 住環境
Research Abstract

The purposes of this research were the exposure assessment of polybrominated diphenyl ethers (PBDEs) from the environment and the risk assessment of PBDEs on humans and animals.
The results of this study clarified : (a) the concentration level of PBDEs from electrical facilities indoor air, (b) exposure assessment of human blood samples of PBDEs, (c) risk using mice. These new findings will help to develop the environmental preventive medicine to decrease the risk by artificial chemicals on future generations.

  • Research Products

    (18 results)

All 2011 2010 2009 2008 Other

All Journal Article (7 results) (of which Peer Reviewed: 4 results) Presentation (9 results) Book (2 results)

  • [Journal Article] 化学物資の次世代への影響-長期晩発影響とエピジェネティック変異による影響-2010

    • Author(s)
      森千里
    • Journal Title

      保健の科学 52

      Pages: 15-19

  • [Journal Article] 臭素系難燃剤による胎児への影響に関する最近の知見2009

    • Author(s)
      川城由紀子、松野義晴、深田秀樹、森千里
    • Journal Title

      医学の歩み 228

      Pages: 785-786

  • [Journal Article] ケミレス"環境医学-化学物質を削減した社会づくりポリ塩化ビフェニル(PCB)を指標とした化学物質の健康診断と削減方法の開発2009

    • Author(s)
      深田秀樹、森千里
    • Journal Title

      医学の歩み 228

      Pages: 785-786

  • [Journal Article] Establishment of sustainable health science for future generations : from a hundred years ago to a hundred years in the future2009

    • Author(s)
      Mori C, Todaka E
    • Journal Title

      Environ. Health Prev.Med. 14

      Pages: 1-6

    • Peer Reviewed
  • [Journal Article] Perinatal Exposure to Brominated Flame Retardants and Polychlorinated Biphenyls in Japan2008

    • Author(s)
      Kawashiro Y, Fukata H, Omori-Inoue M, Kubonoya K, Jotaki T, Takigami H, Sakai S, Mori C
    • Journal Title

      Endocrine Journal 55

      Pages: 1071-1084

    • Peer Reviewed
  • [Journal Article] Strong correlation between the concentration of dioxins and total PCBs in current Japanese people2008

    • Author(s)
      Mori C, Fukata H, Sakurai K, Jotaki T, Todaka E, Saito Y
    • Journal Title

      Chemosphere 73

      Pages: S235-S238

    • Peer Reviewed
  • [Journal Article] New point for evaluation of environmental pollutants including endocrine disrupting chemicals and polybrominated diphenyl ethers (PBDEs) on male reproductive system

    • Author(s)
      C.Mori, H.Miyaso, N.Nakamura, Y.Matsuno Y, E.Todaka
    • Journal Title

      Proceeding book of the 11th International symposium on Spermatology (in press)

    • Peer Reviewed
  • [Presentation] Correlation between Polybrominated Diphenyl Ethers (PBDEs) and Persistent Organic Pollutants (POPs) or Heavy Metals Detected in Umbilical Cords2011

    • Author(s)
      Y.Igoshi, S.Ochiail, E.Todaka, Y.Matsuno, N.Shimojo, Y.Kohno, C.Mori
    • Organizer
      50^<th> Anniversary Annual Meeting & ToxExpo
    • Place of Presentation
      Washington, D.C.USA
    • Year and Date
      2011-03-09
  • [Presentation] The Effect of Neonatal Exposure to Deca-Brominated Diphenyl Ether on Apical Ectoplasmic Specialization Mouse Testis2011

    • Author(s)
      H.Miyaso, Y.Matsuno, M.Komiyama, S.Ochiai, Y.Igoshi, C.Mori
    • Organizer
      50^<th> Anniversary Annual Meeting & ToxExpo
    • Place of Presentation
      Washington, D.C.USA
    • Year and Date
      2011-03-07
  • [Presentation] Analysis Transfer Rate of Congeners of PCBs and OH-PCBS From Mother to Fetus Through Placenta in Human2011

    • Author(s)
      C.Mori, E.Todaka, Y.Matsuno, T.Fujisaki, M.Shimoda, H.Nakaoka, M.Hanazato
    • Organizer
      50^<th> Anniversary Annual Meeting & ToxExpo
    • Place of Presentation
      Washington, D.C.USA
    • Year and Date
      2011-03-07
  • [Presentation] Current fetal exposure level of endocrine disruptors, heavy metals and brominated flame retardants in Japan2010

    • Author(s)
      C.Mori, Y.Matsuno, H.Nakaoka, M.Hanazato, E.Todaka
    • Organizer
      ISES-ISEE 2010
    • Place of Presentation
      Invited, Seoul, Korea
    • Year and Date
      2010-08-30
  • [Presentation] Cohort study on infant atopic dermatitis and fetal exposure to persistent organic pollutants (POPs), heavy metals and brominated flame retardants (BFRs)2010

    • Author(s)
      C.Mori, E.Todaka, Y.Matsuno, H.Nakaoka, M.Hanazato, S. Suzuki, N.Shimojo, Y.Kono
    • Organizer
      The Power of Programming
    • Place of Presentation
      Munchen, Germany
    • Year and Date
      2010-05-07
  • [Presentation] Concentrations of the total PBDEs in Japanese human blood2010

    • Author(s)
      Y.Matsuno, H.Fukata, Y Kawashiro, H.Takigami, H.Nakaoka, E Todaka, C.Mori
    • Organizer
      5th International Symposium on Brominated Flame Retardants (BFR2010)
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-04-08
  • [Presentation] Association between exposure to organochlorines and the occurrence of atopic dermatitis in Japanese infant2009

    • Author(s)
      C.Mori
    • Organizer
      ISES 2009 annual conference : transforming exposure science in the 21st century
    • Place of Presentation
      Minneapolis, Minnesota, USA
    • Year and Date
      2009-11-02
  • [Presentation] Application of health examination system of total PCBs to prevental prenatal and lactational exposure of persistent organic polutants (POPs)2009

    • Author(s)
      C.Mori, H.Fukata
    • Organizer
      3rd WHO international conference on children's health and the environment
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2009-06-08
  • [Presentation] Occurrence and control strategy of POPs-Japan experience2008

    • Author(s)
      Mori C, Todaka E
    • Organizer
      2008 Conference on persistent organic pollutants and dioxin
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2008-09-05
  • [Book] Environmental contaminants and children's health Sustainable health science for future generations2011

    • Author(s)
      森千里, 戸高恵美子
    • Total Pages
      133
    • Publisher
      MARUZEN PLANET Co.,Ltd.
  • [Book] へその緒が語る体内汚染-未来世代を守るために-2008

    • Author(s)
      森千里、戸高恵美子
    • Total Pages
      207
    • Publisher
      技術評論社

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Published: 2012-01-26   Modified: 2016-04-21  

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