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2012 Fiscal Year Final Research Report

Development of predictive-preventive nutritional science for metabolic syndrome in representative high-risk populations in the world

Research Project

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Project/Area Number 20256001
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Eating habits, studies on eating habits
Research InstitutionMukogawa Women's University

Principal Investigator

YAMORI Yukio  武庫川女子大学, 国際健康開発研究所, 教授 (80025600)

Co-Investigator(Renkei-kenkyūsha) NISHIO Hisahide  神戸大学, 大学院・医学研究科, 教授 (80189258)
ICHIKAWA Atsushi  武庫川女子大学, 薬学部, 教授 (10025695)
KINOSHITA Kenji  武庫川女子大学, 薬学部, 教授 (70441219)
MORI Mari  武庫川女子大学, 国際健康開発研究所, 講師 (70399343)
KATO Norihiro  国立国際医療センター研究所, 遺伝子診断治療開発研究部, 部長 (80293934)
KATSUYA Tomohiro  大阪大学, 大学院・医学部, 特任准教授 (30311757)
HAMADA Atsumi  武庫川女子大学, 国際健康開発研究所, 助手 (40541967)
TAGUCHI Takashi  武庫川女子大学, 国際健康開発研究所, 助手 (50449005)
BABA Takako  武庫川女子大学, 国際健康開発研究所, 助手 (50643293)
Project Period (FY) 2008 – 2012
Keywords国際研究交流 / インド,インドネシア,スリランカ,オーストラリア,ブラジル,カナダ,スコットランド / 24 時間尿分析 / マグネシウム / タウリン / 食塩感受性 / 生活習慣病 / 脂質異常症
Research Abstract

WHO-coordinated cardiovascular diseases and alimentary comparisonstudy and newly added studies on high-risk populations indicated magnesium and taurineintake reductions were related with increased risks despite genetic differences,salt-induced blood pressure rise was related with increased heart rate and this bloodpressure rise was significantly lowered by higher taurine intake, vegetable intakeaffected risks significantly through genotypes related to folic acid absorption, and therisks of increasing dyslipidemia were proven to be reduced by a soy intervention study. These findings contributed to the development of nutritional prediction and preventionof lifestyle-related diseases.

  • Research Products

    (24 results)

All 2013 2012 2011 2010

All Journal Article (16 results) (of which Peer Reviewed: 16 results) Presentation (2 results) Book (6 results)

  • [Journal Article] Antithrombotic effect of taurine inhealthy Japanese people may be related to an increased endogenous thrombolytic activity2013

    • Author(s)
      Yamori Y.
    • Journal Title

      Thrombosis Research

      Volume: 131 Pages: 158-161

    • DOI

      DOI:10.1016/j.thromres.2012.09.021

    • Peer Reviewed
  • [Journal Article] Physicalactivity and cardiovascular disease risk factors among young andmiddle-aged men in urban Mwanza2012

    • Author(s)
      Yamori Y.
    • Journal Title

      Tanzania, Pan African Medical Journal

      Volume: 11

    • Peer Reviewed
  • [Journal Article] Serum folate, total homocysteine levels and methylenetetrahydrofolate reductase677C>T polymorphism in young healthyfemale Japanese2012

    • Author(s)
      Yamori Y
    • Journal Title

      Asia Pacific Journalof Clinical Nutrition

      Volume: 21 Pages: 291-295

    • Peer Reviewed
  • [Journal Article] Effects ofcooking using multi-ply cookware onabsorption of potassium and vitamins: arandomized double-blind placebocontrol study2012

    • Author(s)
      Yamori Y.
    • Journal Title

      International Journal ofFood Sciences and Nutrition

      Volume: 63 Pages: 530-536

    • DOI

      DOI: 10.3109/09637486.2011.642342

    • Peer Reviewed
  • [Journal Article] Effects of docosahexaenoic acid supplementation on blood pressure, heart rate, and serum lipids in Scottish men with hypertension and hypercholesterolemia2011

    • Author(s)
      Yamori Y.
    • Journal Title

      International Journal of Hypertension

      Volume: 2011

    • DOI

      DOI: 10.4061/2011/809198

    • Peer Reviewed
  • [Journal Article] Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in East Asians2011

    • Author(s)
      Yamori Y
    • Journal Title

      Nat Genetics

      Volume: 43 Pages: 531-538

    • DOI

      DOI:10.1038/ng.834

    • Peer Reviewed
  • [Journal Article] Possible association of high urinary magnesium and taurine to creatinine ratios with metabolic syndrome risk reduction in Australian aborigianals2011

    • Author(s)
      Yamori Y.
    • Journal Title

      Cardiology Research and Practice

      Volume: 2011 Pages: 1-7

    • DOI

      DOI: 10.4061/2011/235653

    • Peer Reviewed
  • [Journal Article] Hypertension, periodontal disease, and potassium intake in nonsmoking, nondrinker African women on no medication2011

    • Author(s)
      Yamori Y.
    • Journal Title

      International Journal of Hypertension

      Volume: 2011 Pages: 1-6

    • DOI

      DOI: 10.4061/2011/695719

    • Peer Reviewed
  • [Journal Article] Prevalence of cardiovascular disease risk factors among young and middle-aged men in urban Mwanza, Tanzania2011

    • Author(s)
      Yamori Y.
    • Journal Title

      Journal of Public Health

      Volume: 19 Pages: 553-561

    • DOI

      DOI:10.1007/s10389-011-0419-1

    • Peer Reviewed
  • [Journal Article] First direct comparison of platelet reactivity and thrombolytic status between Japanese and Western volunteers: Possible relationship to the "Japanese paradox2011

    • Author(s)
      Yamori Y.
    • Journal Title

      International Journal of Cardiology

      Volume: 152 Pages: 43-48

    • DOI

      DOI: 10.1016/j.ijcard.2010.07.002

    • Peer Reviewed
  • [Journal Article] Taurine in health and diseases: consistent evidence from experimental and epidemiological studies,2010

    • Author(s)
      Yamori Y.
    • Journal Title

      Journal of Biomedical Science

      Volume: 17 Pages: 1-6

    • DOI

      DOI: 10.1186/1423-0127-17-S1-S6

    • Peer Reviewed
  • [Journal Article] Low cardiovascular risks in the middle aged males and females excreting greater 24-hour urinary taurine and magnesium in 41 WHO-CARDIAC study populations in the world2010

    • Author(s)
      Yamori Y.
    • Journal Title

      Journal of Biomedical Science

      Volume: 17 Pages: l1-21

    • DOI

      DOI: 10.1186/1423-0127-17-S1-S21

    • Peer Reviewed
  • [Journal Article] Blood pressure and hypertension are associated with 7 loci in the Japanese population2010

    • Author(s)
      Yamori Y.
    • Journal Title

      Circulation

      Volume: 121 Pages: 2302-2309

    • DOI

      DOI:10.1161/CIRCULATIONAHA.109.904664

    • Peer Reviewed
  • [Journal Article] Deterioration of traditional dietary custom increases the risk of lifestyle-related diseases in young male Africans2010

    • Author(s)
      Yamori Y.
    • Journal Title

      Journal of Biomedical Science

      Volume: 17 Pages: 11-34

    • DOI

      DOI: 10.1186/1423-0127-17-S1-S34

    • Peer Reviewed
  • [Journal Article] Resting heart rate in relation to blood pressure:Results from the World Health Organization-Cardiovascular Disease and Alimentary Comparison Study2010

    • Author(s)
      Yamori Y.
    • Journal Title

      International Journal of Cardiology

      Volume: 145 Pages: 73-74

    • DOI

      DOI: 10.1016/j.ijcard.2009.04.0324

    • Peer Reviewed
  • [Journal Article] Common variants at the GCK, GCKR, G6PC2-ABCB11 and MTNR1B loci are associated with fasting glucose in two Asian populations2010

    • Author(s)
      Yamori Y.
    • Journal Title

      Diabetologia

      Volume: 53 Pages: 299-308

    • DOI

      DOI: 10.1007/s00125-009-1595-1

    • Peer Reviewed
  • [Presentation] Nutritional high risk and population approaches to hypertension Lessons from our studies in Japan and in the world2013

    • Author(s)
      Yamori Y.
    • Organizer
      World Hypertension Congress 2013
    • Place of Presentation
      Halic Congress Center(トルコ)
    • Year and Date
      2013-06-28
  • [Presentation] ベジタリアンの多い南インドにおける生活習慣病のリスク分析2013

    • Author(s)
      家森幸男
    • Organizer
      栄養食糧学会
    • Place of Presentation
      名古屋大学
    • Year and Date
      2013-05-25
  • [Book] ゲノムプラスの栄養学2013

    • Author(s)
      家森幸男
    • Total Pages
      111
    • Publisher
      武庫川女子大学出版部
  • [Book] 武庫川女子大学国際健康開発研究所紀要第4号2012

    • Author(s)
      家森幸男
    • Total Pages
      129
    • Publisher
      武庫川女子大学
  • [Book] 世界一長寿な都市はどこにある2011

    • Author(s)
      家森幸男
    • Total Pages
      214
    • Publisher
      岩波書店
  • [Book] 武庫川女子大学国際健康開発研究所紀要第3号2011

    • Author(s)
      家森幸男
    • Total Pages
      110
    • Publisher
      武庫川女子大学
  • [Book] 遺伝子が喜ぶ長生きごはん2010

    • Author(s)
      家森幸男
    • Total Pages
      203
    • Publisher
      朝日新聞出版
  • [Book] 武庫川女子大学国際健康開発研究所紀要第2号2010

    • Author(s)
      家森幸男
    • Total Pages
      218
    • Publisher
      武庫川女子大学

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Published: 2014-08-29   Modified: 2018-04-24  

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