2011 Fiscal Year Final Research Report
Molecular mechanisms for heat stress-associated skeletal muscle hypertrophy-a possible application of heat stress to sports sciences-
Project/Area Number |
20300218
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Sports science
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Research Institution | Toyohashi Sozo University |
Principal Investigator |
GOTO Katsumasa (山下 勝正) 豊橋創造大学, 保健医療学部, 教授 (70239961)
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Co-Investigator(Kenkyū-buntansha) |
OHNO Yoshitaka 豊橋創造大学, 保健医療学部, 講師 (80440808)
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Co-Investigator(Renkei-kenkyūsha) |
OHIRA Yoshinobu 大阪大学, 大学院・医学系研究科, 教授 (50185378)
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Project Period (FY) |
2008 – 2011
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Keywords | 骨格筋 / 骨格筋可塑性 / 温熱刺激 / ストレス応答 / スポーツ科学 |
Research Abstract |
The purpose of this study was to investigate the molecular mechanisms for heat stress-associated skeletal muscle hypertrophy, and to develop effective and safe physical exercise for a gaining of muscle volume as well as the countermeasure for aging-associated muscle atrophy(sarcopenia). Evidences suggested that stress response plays a key role in skeletal muscle hypertrophy. Heat stress may be a useful tool for not only a gaining of muscle volume but also rehabilitation after sports injuries.
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Research Products
(65 results)
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[Journal Article] Adaptation of Mouse Skeletal Muscle to Long-Term Microgravity in the MDS Mission2012
Author(s)
Sandona, D., Desaphy, J.-F., Camerino, G. M., Bianchini, E., Ciciliot, S., Danieli-Betto, D., Dobrowolny, G., Furlan, S., Germinario, E., Goto, K., Gutsmann, M., Kawano, F., Nakai, N., Ohira, T., Ohno, Y., Picard, A., Salanova, M., Schiffl, G., Blottner
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Journal Title
PLoS ONE
Volume: 7
Pages: 33232
DOI
Peer Reviewed
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[Journal Article] Absence of heat shock transcription factor 1 retards the regrowth of atrophied soleus muscle in mice2011
Author(s)
Yasuhara, K., Ohno, Y., Kojima, A., Uehara, K., Beppu, M., Sugiura, T., Fujimoto, M., Nakai, A., Ohira, Y., Yoshioka, T., and Goto, K.
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Journal Title
J. Appl. Physiol.
Volume: 111
Pages: 1142-1149
DOI
Peer Reviewed
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[Journal Article] Possible role of NF-kB signals in heat-stress-associated increase in protein content of cultured C2C12 cells2011
Author(s)
Ohno, Y., Yamada, S., Sugiura, T., Ohira, Y., Yoshioka, T., and Goto, K.
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Journal Title
Cells Tissues Organs
Volume: 194
Pages: 363-370
DOI
Peer Reviewed
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[Journal Article] Responses of muscle mass, strength and gene transcripts to long-term heat stress in healthy human subjects2011
Author(s)
Goto, K., Oda, H., Kondo, H., Igaki, M., Suzuki, A., Tsuchiya, S., Murase, T., Hase, T., Fujiya, H., Matsumoto, I., Naito, H., Sugiura, T., Ohira, Y., and Yoshioka, T.
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Journal Title
Eur. J. Appl. Physiol.
Volume: 111
Pages: 17-27
DOI
Peer Reviewed
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[Journal Article] Role(s) of mechanical load and satellite cells in the regulation of the size of soleus muscle fibers in rats2010
Author(s)
Ohira, Y., Kawano, F., Wang, X. D., Nakai, N., Ohira, T., Okabe, H., Naito, H., and Goto, K.
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Journal Title
Biol. Sci. Space
Volume: 24
Pages: 135-144
URL
Peer Reviewed
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[Journal Article] A possible role of NF-・B and HSP72 in skeletal muscle hypertrophy induced by heat stress in rats2010
Author(s)
Ohno, Y., Yamada, S., Sugiura, T., Ohira, Y., Yoshioka, T., and Goto, K.
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Journal Title
Gen. Physiol. Biophys.
Volume: 29
Pages: 234-242
DOI
Peer Reviewed
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[Journal Article] Role(s) of gravitational loading during developing period on the growth of rat soleus muscle fibers2010
Author(s)
Kawano, F., Goto, K., Wang, X. D., Terada, M., Ohira, T., Nakai, N., Yoshioka, T., and Ohira, Y.
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Journal Title
J. Appl. Physiol.
Volume: 108
Pages: 676-685
DOI
Peer Reviewed
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[Journal Article] Gravitational unloading inhibits the regenerative potential of atrophied soleus muscle in mice2009
Author(s)
Matsuba, Y., Goto, K., Morioka, S., Naito, T., Akema, T., Hashimoto, N., Sugiura, T., Ohira, Y., Beppu, M., and Yoshioka, T.
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Journal Title
Acta Physiol.
Volume: 196
Pages: 329-339
DOI
Peer Reviewed
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[Journal Article] Administration of granulocyte colony-stimulating factor facilitates the regenerative process of injured mice skeletal muscle via the activation of Akt/GSK3τυsignals2009
Author(s)
Naito, T., Goto, K., Morioka, S., Matsuba, Y., Akema, T., Sugiura, T., Ohira, Y., Beppu, M., and Yoshioka, T.
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Journal Title
Eur. J. Appl. Physiol.
Volume: 105
Pages: 643-651
DOI
Peer Reviewed
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