2010 Fiscal Year Final Research Report
Analysis of the functional network governing cell division and cell differentiation
| Project/Area Number |
20380055
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Tokyo University of Agriculture |
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Principal Investigator |
YOSHIKAWA Hirofumi Tokyo University of Agriculture, 応用生物科学部, 教授 (50175676)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 遺伝子発現 / 細胞分裂 / 脂質合成 / 細胞分化 / クエン酸回路 / 機能ネットワーク |
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| Research Abstract |
Analysis of the physiological significance of the stationary phase cells will contribute to the further understanding of cellular functions and genetic control systems in the viewpoint of functional network. We found an essential gene for lipid synthesis interacted with cell divisional machinery and involved in septum formation. While, a gene in the TCA cycle was found to be essential only for sporulationand was suggested to be a critical factor proceeding to the cell differentiation by sensing energy level of the cell.
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