2010 Fiscal Year Final Research Report
Development of a rotating cerium-anode-equipped microangiographic system to visualize small arteries in major organs in clinical settings.
Project/Area Number |
20390336
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Radiation science
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Research Institution | Tokai University |
Principal Investigator |
MORI Hidezo Tokai University, 医学部, 教授 (90146598)
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Project Period (FY) |
2008 – 2010
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Keywords | 放射線 / X線・粒子線 / 循環器・高血圧 / 脳神経疾患 / 移植・再生医療 |
Research Abstract |
Conventional angiography can not visualize arterioles with a diameter range of 20-200μm. In other words the conventional system is not appropriate to evaluate pathophysiology of intramural small coronary arteries and/or cerebaral perforating arterie (diameter of 50-300μm) in clinical settings. In the present study, we developed a rotating cerium-anode- and a high-heat unit (5MHU) equipped-in-hospital microangiographic system and confirmed its performances in animal experiments.
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[Journal Article] Magnification Embossed Radiography Utilizing Image-Shifting Subtraction Program2010
Author(s)
Akihiro Osawa, Manabu Watanabe,Eiichi Sato, Hiroshi Matsukiyo, Toshiyuki Enomoto, Jiro Nagao, Purkhet Abderyim, Katsuo Aizawa, Etsuro Tanaka, Hidezo Mori, Toshiaki Kawai, Akira Ogawa, Kiyomi Takahashi, Shigehiro Sato, Jun Onagawa
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Journal Title
Jpn J Appl Phys. 49
Pages: 037001-7
Peer Reviewed
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[Journal Article] Energy-Discriminating Gadolinium K-Edge X-ray Computed Tomography System2010
Author(s)
Hiroshi Matsukiyo, Manabu Watanabe, Eiichi Sato, Akihiro Osawa, Toshiyuki Enomoto, Jiro Nagao, Purkhet Abderyim, Katsuo Alzawa, Keitaro Hitomi, Etsuro Tanaka, Hidezo Mori, Toshiaki Kawai, Akira Ogawa, Kiyomi Takahashi, Shigehiro Sato, Jun Onagawa
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Journal Title
Jpn J Appl Phys. 49
Pages: 027001-6
Peer Reviewed
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[Journal Article] Year-long upregulation of connexin43 in rabbit hearts by heavy ion irradiation2010
Author(s)
M.Amino, K.Yoshioka, D.Fujibayashi, T.Hashida, Y.Furusawa, W.Zareba, Y.Ikari, E.Tanaka, H.Mori, S.Inokuchi, I.Kodama, T.Tanabe
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Journal Title
Am J Physiol Heart Circ Physiol. 298
Pages: H1014-H1021
Peer Reviewed
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[Journal Article] A trial for fine and low-dose imaging of biological specimens using quasi-monochromatic laser-Compton X-rays2009
Author(s)
K.Yamada, R.Kuroda, H.Toyakawa, H.Ikeura-Sekiguchi, M.Yasumoto, M.Koike, F.Sakai, K.Mori, H.Mori, N.Fukuyama, E.Sato
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Journal Title
Nuclear Instruments and Methods in Physics Research. A608
Pages: S7-S10
Peer Reviewed
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[Journal Article] Embossed radiography utilizing energy subtraction2009
Author(s)
A.Osawa, M.Watanabe, E.Sato, H.Matsukiyo, T.Enomoto, J.Nagao, P.Abderyim, K.Aizawa, E.Tanaka, H.Mori, T.Kawai, S.Ehara, S.Sato, A.Ogawa, J.Onagawa
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Journal Title
Radiol Phys Technol. 2
Pages: 77-86
Peer Reviewed
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[Journal Article] X-ray fluorescence camera for imaging of iodine media in vivo2009
Author(s)
H.Matsukiyo, M.Watanabe, E.Sato, A.Osawa, T.Enomoto, J.Nagao, P. Abderyim, K.Aizawa, E.Tanaka, H.Mori, T.Kawai, S.Ehara, S.Sato, A.Ogawa, J.Onagawa
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Journal Title
Radiol Phys Technol. 2
Pages: 46-53
Peer Reviewed
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[Journal Article] X-ray Spectra from a Brass-target Plasma Triode2008
Author(s)
E.Sato, H.Obara, T.Enomoto, E.Tanaka, H.Mori, T.Kawai, T.Ichimaru, A.Ogawa, S.Sato, K.Takayama, J.Onagawa
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Journal Title
Jpn.J.Med.Phys. Vol.27.No.4
Pages: 163-171
Peer Reviewed
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[Presentation] Cardioprotective Effects of Hydrogen Peroxide and Erythropoietin during Acute Coronary Occlusionin Canine Coronary Native Collateral Microvessels in vivo2010
Author(s)
T.Yada, H.Shimokawa, O.Hiramatsu, M.Satoh, N.Kashihara, Y.Shinozaki, H.Mori, A.Takaki, M.Goto, Y.Ogasawara, F.Kajiya
Organizer
第74回日本循環器学会総会・学術集会
Year and Date
20100000
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[Presentation] Development of Microangiographic Systems for Visualization, Quantification and Therapeutic Evaluation of Angiogenic Vessels2009
Author(s)
T.Fujii, N.Fukuyama, Y.Ikeya, E.Tanaka, T.Sekka, Y.Shinozaki, K.Yamada, K.Umetani, K.Hyodo, E.Sato, K.Fukushima, T.Tanabe, H.Mori
Organizer
11th International Symposium on Anti-Angiogenic Agents.
Place of Presentation
San Diego (United States) February
Year and Date
20090500-20090700
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[Presentation] Development of advanced quantum-beam sources and their applications as sophisticated imaging tools2008
Author(s)
K.Yamada, R.Kuroda, H.Toyokawa, H.Ikeura-Sekiguchi, M.Yasumoto, N.Sei, H.Ogawa, M.Koike, R.Suzuki, F.Sakai, K.Mori, H.Mori, N.Fukuyama, E.Sato
Organizer
Compton Sources for X/gamma Rays : Physics and Applications
Place of Presentation
in Italy
Year and Date
20080000
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[Presentation] Cardioprotective Effect of Hydrogen Peroxide and Erythropoietin During Acute Coronary Occlusion in Canine Coronary Native Collateral Microvessel ; in vivo
Author(s)
T.Yada, H.Shimokawa, O.Hiramatsu, M.Satoh, N.Kashihara, Y.Shinozaki, H.Mori, A.Takaki, M.Goto, H.Nakamoto, Y.Ogasawara, F.Kajiya
Place of Presentation
American Heart Association (Orland, Florida)
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[Remarks] ホームページ等