2010 Fiscal Year Final Research Report
Identification of Risk Factors Related to Poor Angiogenic Potential of Bone Marrow Cells from Different Patients
| Project/Area Number |
20390370
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Yamaguchi University |
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Principal Investigator |
HAMANO Kimikazu Yamaguchi University, 大学院・医学系研究科, 教授 (60263787)
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| Co-Investigator(Kenkyū-buntansha) |
HARADA Noriaki 山口大学, 大学院・医学系研究科, 教授 (70116747)
MIKAMO Akihito 山口大学, 医学部・附属病院, 講師 (30372709)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 骨髄細胞 / 血管再生 / 治療効果 / 細胞移植 / 再生医療 / 加齢 / 腎不全 / 貧血 |
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| Research Abstract |
The implantation of autologous bone marrow cells has been used for the ischemic diseases. However, the outcomes of cell therapy obviously vary among patients. In this study, we have identified the risk factors related to poor angiogenic potential of bone marrow cells and developed a new scoring system to predict their angiogenic potential for the treatment of ischemic diseases.
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[Journal Article] Ischemic pre-conditioning enhances the mobilization and recruitment of bone marrow stem cells to protect against ischemia/reperfusion injury in the late phase.2009
Author(s)
Kamota T, Li TS, Morikage N, Murakami M, Ohshima M, Kubo M, Kobayashi T, Mikamo A, Ikeda Y, Matsuzaki M, Hamano K.
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Journal Title
J Am Coll Cardiol. 53(19)
Pages: 1814-1822
Peer Reviewed
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[Presentation] Identification of risk factors related to poor angiogenic potency of bone marrow cells from different patients.2008
Author(s)
Li TS, Kubo M, Ueda K, Murakami M, Ohshima M, Kobayashi T, Tanaka T, Shirasawa B, Mikamo A, Hamano K
Organizer
American Heart Association 2008 Scientific Sessions
Place of Presentation
New Orleans, Ernest N.Morial Convention Center, USA
Year and Date
2008-11-11
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