2010 Fiscal Year Final Research Report
The development of the new therapy aim to decrease the incidence of cerebrovascular disease based on suppression arterial sclerosis lesion.
| Project/Area Number |
20390390
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Iwate Medical University |
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Principal Investigator |
OGAWA Akira Iwate Medical University, 学長 (10204067)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHIDA Kenji 岩手医科大学, 医学部, 助教 (10316367)
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| Co-Investigator(Renkei-kenkyūsha) |
OGASAWARA Kuniaki 岩手医科大学, 医学部, 教授 (00305989)
KUBO Yoshitaka 岩手医科大学, 医学部, 講師 (00316366)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 脳血管障害 |
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| Research Abstract |
About higher brain function disorder development after the cerebral reperfusion, we could confirm that a neuronal loss occurred by a study using iomazenil SPECT, and it became clear to correlate with postoperative higher brain function disorder. A reduction flow velocity of transcranial Doppler and cerebrovascular reserve capacity significantly correlated with cerebral infarction development with the carotid endoarterectomy, and it became clear that we could foresee in SPECT and MRA. The hyperemia after reperfusion that reflected ischemic degree.
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[Journal Article] Brain temperature measured by using proton MR spectroscopy predicts cerebral hyperperfusion after carotid endarterectomy.2010
Author(s)
Murakami T, Ogasawara K, Yoshioka Y, Ishigaki D, Sasaki M, Kudo K, Aso K, Nishimoto H, Kobayashi M, Yoshida K, Ogawa A
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Journal Title
Radiology 256(3)
Pages: 924-931
Peer Reviewed
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[Journal Article] Screening the single nucleotide polymorphisms in patients with internal carotid artery stenosis by oligonucleotide-based custom DNA array.2009
Author(s)
Nakai K, Oyanagi M, Hitomi J, Ogasawara K, Inoue T, Kobayashi M, Nakai K, Suwabe A, Habano W, Baba T, Yoshida H, Ogawa A
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Journal Title
Bioinform Biol Insights. 1
Pages: 63-69
Peer Reviewed
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[Journal Article] Elevated concentrations of sphingosylphosphorylcholine in cerebrospinal fluid after subarachnoid hemorrhage : a possible role as a spasmogen.2009
Author(s)
Kurokawa T, Yumiya Y, Fujisawa H, Shirao S, Kashiwagi S, Sato M, Kishi H, Miwa S, Mogami K, Kato S, Akimura T, Soma M, Ogasawara K, Ogawa A, Kobayashi S, Suzuki M.
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Journal Title
J Clin Neurosci. 16(8)
Pages: 1064-1068
Peer Reviewed
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[Journal Article] Brain temperature measured using proton MR spectroscopy detects cerebral hemodynamic impairment in patients with unilateral chronic major cerebral artery steno-occlusive disease : comparison with positron emission tomography.2009
Author(s)
Ishigaki D, Ogasawara K, Yoshioka Y, Chida K, Sasaki M, Fujiwara S, Aso K, Kobayashi M, Yoshida K, Terasaki K, Inoue T, Ogawa A
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Journal Title
Stroke 40(9)
Pages: 3012-3016
Peer Reviewed
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[Journal Article] Simple assessment of cerebral hemodynamics using single-slab 3D time-of-flight MR angiography in patients with cervical internal carotid artery steno-occlusive diseases: comparison with quantitative perfusion single-photon emission CT.2009
Author(s)
Hirooka R, Ogasawara K, Inoue T, Fujiwara S, Sasaki M, Chida K, Ishigaki D, Kobayashi M, Nishimoto H, Otawara Y, Tsushima E, Ogawa A
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Journal Title
AJNR Am J Neuroradiol. 30(3)
Pages: 559-563
Peer Reviewed
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