2011 Fiscal Year Final Research Report
Evaluation of relationships between root resorption accompanied with orthodontic tooth movement and cell death of cementum-related cells
| Project/Area Number |
20390525
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Health Sciences University of Hokkaido |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TAKUMA Taishin 北海道医療大学, 歯学部, 教授 (40095336)
TORIYA Naoko 北海道医療大学, 歯学部, 助教 (20433435)
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| Project Period (FY) |
2008 – 2011
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| Keywords | 歯根吸収 / 歯の移動 / セメント芽細胞 / セメント細胞 / 細胞死 |
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| Research Abstract |
The purpose of this study was to clarify the biological mechanism of root resorption caused by orthodontic tooth movement. 8-week-old Wistar rats were used as an experimental animal model. The unilateral first molar was moved buccaly by a cantilever-type Ni-Ti wire(. 012 inch in diameter). The initial force was adjusted to 20 gf. The results indicate that cell death of cementoblasts of acellular cementum accompanied by orthodontic tooth movement may induce resorptive activities of odontoclasts, which suggest relationship between cell death of cementoblasts and root resorption.
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[Journal Article] High frequency of hypermethylation of p14, p15 and p16 in oral pre-cancerous lesions associated with betel-quid chewing in Sri Lanka2008
Author(s)
Takeshima M, Saitoh M, Kusano K, Nagayasu H, Kurashige Y, Malsantha M, Arakawa T, Takuma T, Chiba I, Kaku T, Shibata T, Abiko Y.
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Journal Title
J Oral Pathol Med
Volume: Vol.37
Pages: 475-479
Peer Reviewed
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[Presentation] 歯並びと健康2011
Author(s)
溝口到
Organizer
第31回北海道学校歯科保健研究大会
Place of Presentation
北海道歯科医師会館(北海道)
Year and Date
2011-10-14
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