2010 Fiscal Year Final Research Report
Building management systems with highly predictive of periodontal disease
| Project/Area Number |
20390535
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
TANAKA Muneo Osaka University, 歯学部附属病院, 講師 (90263300)
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| Co-Investigator(Kenkyū-buntansha) |
OJIMA Miki 大阪大学, 大学院・歯学研究科, 助教 (20263303)
SHIZUKUISHI Satoshi 大阪大学, 大学院・歯学研究科, 教授 (00028789)
NISHIDA Nobuko 大阪大学, 歯学部附属病院, 医員 (80456946)
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| Project Period (FY) |
2008 – 2010
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| Keywords | メタボリックシンドローム / 歯周病 / 糖尿病 / 動脈硬化性疾患 |
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| Research Abstract |
The purpose of this investigation was to examine the association of periodontal disease and various components of metabolic syndrome. High blood sugar, reduced HDL-Cholesterol and elevated triglycerides were significantly associated with number of teeth as risk indicators. High blood pressure and periodontitis were significantly associated with macrovascular disease(s) as risk indicators. Levels of the inflammatory biomarkers in the subjects with periodontitis increased meaningfully in comparison with the subjects without periodontitis. Periodontal disease was involved in atherosclerotic disease in diabetes. Diabetic patients with periodontitis has significantly higher levels of 8-isopurosutan.
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[Journal Article] Fusobacterium nucleatum envelope protein FomA is immunogenic and binds to the salivary statherin-derived peptide.2010
Author(s)
Nakagaki, H. Sekine, S., Terao, Y., Toe, M., Tanaka, M., Ito, H. O., Kawabata, S., Shizukuishi, S., Fujihashi. K., Kataoka, K.
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Journal Title
Infection and Immunity 78
Pages: 1185-1192
Peer Reviewed
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[Journal Article] Association of ALDH2 genotypes with periodontitis progression.2010
Author(s)
Nishida, N., Tanaka, M., Sekine, S., Takeshita, T., Nakayama, K., Morimoto, K., Shizukuishi, S.
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Journal Title
Journal of Dental Research 89
Pages: 138-142
Peer Reviewed
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