Epidemiological study on mosquito-borne flavivirus infection inGuangdong Province, China

2012 Fiscal Year Final Research Report

• Project/Area Number: 20405040
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 海外学術
• Research Field: Applied veterinary science
• Research Institution: Kyoto Sangyo University (2011-2012); Hokkaido University (2008-2010)
• Principal Investigator: MAEDA Akihiko 京都産業大学, 総合生命科学部, 教授 (70333359)
• Co-Investigator(Kenkyū-buntansha): MAEDA Junko 北海道大学, 大学院・獣医学研究科, 客員研究員 (70399989)
• Research Collaborator: KE Chang-wen 中国・広東省, CDC, 所長 ; JIANG Shu 中国・広東省, CDC, 研究員
• Project Period (FY): 2008 – 2012
• Keywords: 蚊媒介性感染症 / フラビウイルス / 中国 / 広東省 / 疫学調査 / 日本脳炎ウイルス / デングウイルス / ウエストナイルウイルス

Research Abstract

The outbreak of mosquito-borne flavivirus infection caused by recent world-globalization and global-warming, is one of big concerns on world public health. In this study, we developed a new protocol of differential serodiagnosis for flavivirus infection using molecular biological techniques. And we performed an epidemiological study on flavivirus infection in Guangdong province, China. We also analyzed the interrelation of an outbreak of flavivirus infection and meteorological conditions in this province.

Research Products

• [Journal Article] Review of diagnostic plaque reduction neutralization tests for flavivirus infection (2013)
  • Author(s): Maeda, A., and Maeda, J.
  • Journal Title: Vet. J. Volume: 195 Pages: 33-40
  • DOI: doi:10.1016/j.tvjl.2012.08.019.
  • Peer Reviewed
• [Journal Article] Molecular characterization of the E gene of dengue virus type 1 isolated in Guangdong Province, China, in 2006 (2009)
  • Author(s): Zheng, K., Zhou, H.-Q., Yan, J., Ke, C.-W. , Maeda, A., Maeda, J., Takashima, I., Kurane, I., Ma, H., and Xie, X.-M.
  • Journal Title: Epidem. Inf. Volume: 137 Pages: 73-78
  • DOI: doi:10.1017/S0950268808000617.
  • Peer Reviewed
• [Journal Article] A PCR-based protocol for generating West Nile virus replicons (2008)
  • Author(s): Maeda, J., Takagi, H., Hashimoto, S., Kurane, I., and Maeda, A.
  • Journal Title: J. Virol. Methods Volume: 148 Pages: 244-252
  • DOI: doi:10.1016/j.jviromet.2007.12.005.
  • Peer Reviewed
• [Presentation] 中国・広東省の1978-2010年におけるデングウイルス感染症の流行調査 (2011)
  • Author(s): 前田秋彦、Chang-Wen,Ke,JiangShu,倉根一郎
  • Organizer: 第18回トガ・フラビ・ぺスチウイルス研究会
  • Place of Presentation: 東京
  • Year and Date: 2011-11-11
• [Presentation] Epidemiological study of mosquito-borne diseases in Guangdong province, China (2010)
  • Author(s): Maeda, A., and Ke, ChangWen
  • Organizer: WHO meeting
  • Place of Presentation: Guangzhou, China
  • Year and Date: 2010-10-12
• [Presentation] ウエストナイルウイルスと日本脳炎ウイルスの鑑別中和試験法の開発 (2008)
  • Author(s): 前田潤子、村田亮、苅和宏明、倉根一郎、高島郁夫、前田秋彦
  • Organizer: 第146回日本獣医学会
  • Place of Presentation: 宮崎
  • Year and Date: 2008-09-24
• [Book] Epidemiological study on Flaviviruses in Guangdong province, China,2005-2007. (2010)
  • Author(s): Ma, H., Ke, C.-W., Maeda, J., Takashima,I., Kurane, I., and Maeda, A.
  • Total Pages: 89-101
  • Publisher: Ed. Maeda, A., RESEARCH SIGNPOST, India