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2010 Fiscal Year Final Research Report

Significance of sleep for memory formation and storage in primates.

Research Project

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Project/Area Number 20500356
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Neurophysiology and muscle physiology
Research InstitutionUniversity of Toyama

Principal Investigator

TAMURA Ryoi  University of Toyama, 大学院・医学薬学研究部(医学), 教授 (60227296)

Co-Investigator(Kenkyū-buntansha) EIFUKU Satoshi  富山大学, 大学院・医学薬学研究部(医学), 准教授 (70262508)
Co-Investigator(Renkei-kenkyūsha) SUGIMORI Michiya  富山大学, 大学院・医学薬学研究部(医学), 助教 (20464026)
Project Period (FY) 2008 – 2010
Keywords認知 / 記憶
Research Abstract

In the present study we recorded eye movements, muscle activities, scalp EEG, hippocampal EEG and hippocampal unit activities in the monkey during nocturnal sleep, and analyzed correlation between sleep stages and hippocampal neural activities in order to clarify the functional significant of sleep in the formation and storage of memory in primates. As a results we found that low frequency components of hippocampal EEG increased during non-REM sleep (a period in which memory consolidation is thought to be occur) accompanied by increases in hippocampal activities such as ripples and unit activities. These changes in hippocampal neural activity could be the neural substrate for memory consolidation.

  • Research Products

    (26 results)

All 2011 2010 2009 2008 Other

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (19 results) Remarks (1 results)

  • [Journal Article] Short-term synaptic plasticity in the dentate gyros of monkeys.2011

    • Author(s)
      Tamura R, Nishida H, Eifuku S, Nagao K, Fushiki H, Watanabe Y, Ono T
    • Journal Title

      PLoS ONE 6

      Pages: e20006

    • Peer Reviewed
  • [Journal Article] A method for recording evoked local field potentials in the primate dentate gyros in vivo.2011

    • Author(s)
      Tamura R, Eifuku S, Uwano T, Sugimori M, Uchiyama K, Ono T
    • Journal Title

      Hippocampus 21

      Pages: 565-574

    • Peer Reviewed
  • [Journal Article] Neural representations of personally familiar and unfamiliar faces in the anterior inferior temporal cortex of monkeys.2011

    • Author(s)
      Eifuku S, De Souza WC, Nakata R, Ono T, Tamura R
    • Journal Title

      PLoS ONE 6

      Pages: e18913

    • Peer Reviewed
  • [Journal Article] Neural correlates of associative face memory in the anterior inferior temporal cortex of monkeys.2010

    • Author(s)
      Eifuku S, Nakata R, Sugimori M, Ono T, Tamura R.
    • Journal Title

      J Neurosci 30

      Pages: 15085-15096

    • Peer Reviewed
  • [Journal Article] Face perception in its neurobiological and social context.2008

    • Author(s)
      De Souza, WC, Feitosa, MAG, Eifuku S, Tamura R, Ono T
    • Journal Title

      Psychol Neurosci 1

      Pages: 15-20

    • Peer Reviewed
  • [Journal Article] 覚醒下ラット島皮質の味覚応答特性2008

    • Author(s)
      田村了以, 上野照子, 小野武年
    • Journal Title

      日本味と匂学会誌 15

      Pages: 337-340

    • Peer Reviewed
  • [Presentation] サル海馬歯状回とCA1の睡眠脳波2010

    • Author(s)
      西田悠, 永福智志, 永尾薫, 伏木宏彰, 渡邉行雄, 田村了以
    • Organizer
      第19回「海馬と高次脳機能」学会
    • Place of Presentation
      金沢
    • Year and Date
      20101120-20101121
  • [Presentation] サル前部下側頭皮質における個人的親近性のニューロン表現2010

    • Author(s)
      永福智志, De Souza WC, 中田龍三郎, 小野武年, 田村了以
    • Organizer
      第19回「海馬と高次脳機能」学会
    • Place of Presentation
      金沢
    • Year and Date
      20101120-20101121
  • [Presentation] Neural basis for associative face memory in the anterior inferior temporal cortex of macaque monkeys.2010

    • Author(s)
      永福智志, 中田龍三郎, 大門良男, 小野武年, 田村了以
    • Organizer
      40th Ann Meet Soc Neurosci
    • Place of Presentation
      San Diego.
    • Year and Date
      20101114-20101119
  • [Presentation] サルの海馬シータ波と睡眠ステージ2010

    • Author(s)
      田村了以, 西田悠, 永福智志, 永尾薫, 伏木宏彰, 渡邉行雄
    • Organizer
      第57回中部日本生理学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      20101015-20101016
  • [Presentation] 霊長類の海馬脳波-睡眠ステージ相関2010

    • Author(s)
      田村了以, 西田悠, 永福智志, 永尾薫, 伏木宏彰, 渡邉行雄
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      20100902-20100904
  • [Presentation] サル前部下側頭皮質における「顔」の連合記憶の神経機構2010

    • Author(s)
      永福智志, 大門良男, 中田龍三郎, 杉森道也, 小野武年, 田村了以
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      20100902-20100904
  • [Presentation] サルの海馬脳波と睡眠ステージ2010

    • Author(s)
      田村了以, 西田悠, 永福智志, 北村貴志, 伏木宏彰, 渡邉行雄
    • Organizer
      第87回日本生理学会大会
    • Place of Presentation
      盛岡
    • Year and Date
      20100519-20100521
  • [Presentation] サル前部下側頭皮質における「顔」の連合記憶の神経基盤2010

    • Author(s)
      永福智志, 中田龍三郎, 大門良男, 杉森道也, 小野武年, 田村了以
    • Organizer
      第87回日本生理学会大会
    • Place of Presentation
      盛岡
    • Year and Date
      20100519-20100521
  • [Presentation] サルの海馬脳波と睡眠ステージ2009

    • Author(s)
      西田悠, 永福智志, 杉森道也, 北村貴志, 伏木宏彰, 渡辺行雄, 田村了以
    • Organizer
      第56回中部日本生理学会
    • Place of Presentation
      金沢
    • Year and Date
      20091204-20091205
  • [Presentation] 歯状回の成体神経新生に対する貫通路高頻度刺激の影響2009

    • Author(s)
      小座野紘子, 杉森道也, 上野照子, 永福智志, 田村了以
    • Organizer
      第18回「海馬と高次脳機能」学会
    • Place of Presentation
      金沢
    • Year and Date
      20091121-20091122
  • [Presentation] サル海馬の睡眠脳波2009

    • Author(s)
      西田悠, 永福智志, 北村貴志, 伏木宏彰, 渡辺行雄, 田村了以
    • Organizer
      第18回「海馬と高次脳機能」学会
    • Place of Presentation
      金沢
    • Year and Date
      20091121-20091122
  • [Presentation] Neural organization for associative temporal cortex.2009

    • Author(s)
      永福智志, 大門良男, 中田龍三郎, 杉森道也, 小野武年, 田村了以
    • Organizer
      The 39th Ann Meet Soc Neurosci
    • Place of Presentation
      Chicago.
    • Year and Date
      20091017-20091021
  • [Presentation] ラット歯状回における神経新生への反復刺激後長期増強誘導の影響2009

    • Author(s)
      小座野紘子, 杉森道也, Woomi Y., 上野照子, 永福智志, 田村了以
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      20090916-20090918
  • [Presentation] サル前部下側頭皮質における「顔」の連合記憶の神経基盤2009

    • Author(s)
      永福智志, 大門良男, 中田龍三郎, 杉森道也, 小野武年, 田村了以
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      20090916-20090918
  • [Presentation] Long-term synaptic plasticity induced in the primate hippocampus.2009

    • Author(s)
      田村了以, 永福智志, 杉森道也, 上野照子, 小野武年
    • Organizer
      The 36th Congr IUPS
    • Place of Presentation
      Kyoto.
    • Year and Date
      20090729-20090801
  • [Presentation] Neural basis of associative memory of faces in the monkey anterior inferior temporal cortex.2009

    • Author(s)
      Eifuku S, Daimon Y, De Souza WC, Sugimori M, Ono T, Tamura R.
    • Organizer
      The 36th Congr IUPS
    • Place of Presentation
      Kyoto.
    • Year and Date
      20090729-20090801
  • [Presentation] サル脳における顔表象の探求2009

    • Author(s)
      永福智志, 中田龍三郎, 杉森道也, 小野武年, 田村了以
    • Organizer
      第39回日本臨床神経生理学会学術大会
    • Place of Presentation
      北九州
    • Year and Date
      2009-11-19
  • [Presentation] Characteristics of synaptic plasticity in the dentate gyrus of monkeys.2008

    • Author(s)
      田村了以, 杉森道也, 永福智志, 上野照子, 小野武年
    • Organizer
      2nd WFSBP Asia-Pacific Congr & 30th Ann Meet JSBP
    • Place of Presentation
      Toyama.
    • Year and Date
      20080911-20090913
  • [Presentation] サル海馬体における神経可塑性2008

    • Author(s)
      田村了以, 杉森道也, 北村貴志, 永福智志, 上野照子, 小野武年
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京
    • Year and Date
      20080709-20080711
  • [Remarks] ホームページ等

    • URL

      http://www.med.u-toyama.ac.jp/ins/index-j.html

URL: 

Published: 2012-01-26   Modified: 2016-04-21  

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